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Table 1 Clinical and biochemical data at the time of index liver biopsy

From: Long term follow-up and liver-related death rate in patients with non-alcoholic and alcoholic related fatty liver disease

Baseline End of follow-up
  NAFLD group AFLD group p-value NAFLD group AFLD group p-value
n = 151 n = 94   n = 151 n = 94
Gender (F/M) 105/46 31/63 <0.001    
Female% 70% 33%     
  Mean (sd) or Median (IQR) Mean (sd) or Median (IQR)     
Age (years) 54 (14.7) 51 (13.5) NS    
BMI (kg/m2) 29 (26–32) 29 (25–32) NS    
AST (U/L) 47 (32–63) 76 (44–157) <0.001 48 (36; 28–46) 91 (46; 28–93) 0.05
ALT (U/L) 69 (44–102) 109 (58–198) 0.001 44 (36; 26–52) 67 (45; 27–75) 0.04
Bilirubin (μmol/L) 10 (7-15) 12 (9-21) 0.01 14 (9; 7–18) 49 (11; 9–21) NS
ALP (U/L) 197 (135–320) 179 (134–280) NS 196 (122; 87–157) 172 (119; 77–179) NS
Prothrombin time (sec) 13 (12-14) 14 (13-15) 0.02 16 (14; 13–17) 16 (14; 13–17) NS
Albumin (g/L) 40 (36–44) 39 (32–41) NS 37 (39; 33–42) 35 (37; 28–41) NS
Platelets (x109/L) 265 (92.9) 228 (83.3) 0.006 235 (238; 170–281) 219 (222; 152–265) NS
Random blood glucose (mmol/L) 6 (5-7) 6 (5-7) NS 7 (6; 5–7) 7 (6; 5–7) NS
Cholesterol (mmol/L) 6 (5,6) 5 (5-7) NS 5 (5; 4–6) 5(5; 4–6) NS
Triglycerides (mmol/L) 2 (1-3) 2 (1-3) NS 2 (2; 1–2) 2 (2; 1–2) NS
MCV (fL) 90 (6.1) 95 (7.2) <0.001 90 (90; 87–94) 95 (95; 90–105) <0.001
  1. Abbreviations: F female, M male, BMI body mass index, AST aspartate aminotransferase, ALT alanine transaminase, ALP alkaline phosphatase, MCV mean corpuscular volume, NS not significant. Mean (sd) is shown for normally distributed variables, but median (IQR) for other variables. Obesity was defined as BMI ≥ 30 (kg/m).