|
Baseline
|
End of follow-up
|
|---|
| |
NAFLD group
|
AFLD group
|
p-value
|
NAFLD group
|
AFLD group
|
p-value
|
|---|
|
n = 151
|
n = 94
| |
n = 151
|
n = 94
|
|---|
|
Gender (F/M)
|
105/46
|
31/63
|
<0.001
| | | |
|
Female%
|
70%
|
33%
| | | | |
| |
Mean (sd) or Median (IQR)
|
Mean (sd) or Median (IQR)
| | | | |
|
Age (years)
|
54 (14.7)
|
51 (13.5)
|
NS
| | | |
|
BMI (kg/m2)
|
29 (26–32)
|
29 (25–32)
|
NS
| | | |
|
AST (U/L)
|
47 (32–63)
|
76 (44–157)
|
<0.001
|
48 (36; 28–46)
|
91 (46; 28–93)
|
0.05
|
|
ALT (U/L)
|
69 (44–102)
|
109 (58–198)
|
0.001
|
44 (36; 26–52)
|
67 (45; 27–75)
|
0.04
|
|
Bilirubin (μmol/L)
|
10 (7-15)
|
12 (9-21)
|
0.01
|
14 (9; 7–18)
|
49 (11; 9–21)
|
NS
|
|
ALP (U/L)
|
197 (135–320)
|
179 (134–280)
|
NS
|
196 (122; 87–157)
|
172 (119; 77–179)
|
NS
|
|
Prothrombin time (sec)
|
13 (12-14)
|
14 (13-15)
|
0.02
|
16 (14; 13–17)
|
16 (14; 13–17)
|
NS
|
|
Albumin (g/L)
|
40 (36–44)
|
39 (32–41)
|
NS
|
37 (39; 33–42)
|
35 (37; 28–41)
|
NS
|
|
Platelets (x109/L)
|
265 (92.9)
|
228 (83.3)
|
0.006
|
235 (238; 170–281)
|
219 (222; 152–265)
|
NS
|
|
Random blood glucose (mmol/L)
|
6 (5-7)
|
6 (5-7)
|
NS
|
7 (6; 5–7)
|
7 (6; 5–7)
|
NS
|
|
Cholesterol (mmol/L)
|
6 (5,6)
|
5 (5-7)
|
NS
|
5 (5; 4–6)
|
5(5; 4–6)
|
NS
|
|
Triglycerides (mmol/L)
|
2 (1-3)
|
2 (1-3)
|
NS
|
2 (2; 1–2)
|
2 (2; 1–2)
|
NS
|
|
MCV (fL)
|
90 (6.1)
|
95 (7.2)
|
<0.001
|
90 (90; 87–94)
|
95 (95; 90–105)
|
<0.001
|
-
Abbreviations: F female, M male, BMI body mass index, AST aspartate aminotransferase, ALT alanine transaminase, ALP alkaline phosphatase, MCV mean corpuscular volume, NS not significant. Mean (sd) is shown for normally distributed variables, but median (IQR) for other variables. Obesity was defined as BMI ≥ 30 (kg/m).
