Table 1 CD24 and CD44 expressions in gastric carcinomas according to clinicopathological parameters
CD24 positive rate n (%) | P value | CD44 positive rate n (%) | P value | |
|---|---|---|---|---|
Gender | ||||
Male (n=221) | 92(41.6) | 0.148 | 133(60.2) | 0.835 |
Female (n=69) | 22(31.9) | 45(65.2) | ||
Age(y) | ||||
≤60 (n=127) | 48(37.8) | 0.435 | 85(66.9) | 0.087 |
>60 (n=163) | 69(42.3) | 93(57.0) | ||
H.pylori infection (n=103) | ||||
Positive (n=67) | 24(35.8) | 0.096 | 48(71.6) | 0.815 |
Negative (n=36) | 19(52.8) | 25(69.4) | ||
Lauren classification | ||||
Intestinal type (n=104) | 42(40.3) | 0.965 | 67(64.4) | 0.168 |
Diffuse type (n=186) | 77(41.3) | 103(55.3) | ||
WHO classification | ||||
Papillary adenocarcinoma (n=4) | 1(25.0) | 0.906 | 4(100.0) | 0.064 |
Tubular adenocarcinoma | ||||
Well (n=1) | 0(0.0) | 0(0.0) | ||
Moderate (n=98) | 30(30.6) | 49(50.0) | ||
Poor (n=153) | 47(30.7) | 87(56.9) | ||
Mucinous adenocarcinoma (n=27) | 7(25.9) | 13(48.1) | ||
Poorly cohesive carcinomas (Signet ring cell carcinomas) (n=7) | 1(14.3) | 1(14.3) | ||
Lymph-vascular invasion | ||||
Absent (n=134) | 56(41.8) | 0.642 | 72(53.7) | 0.013 |
Present (n=156) | 61(39.1) | 106(67.9) | ||
TNM stage | ||||
I (n=23) | 10(43.5) | 0.844 | 16(69.6) | 0.559 |
II (n=47) | 19(40.4) | 32(68.1) | ||
III (n=187) | 77(41.2) | 110(58.9) | ||
IV (n=33) | 11(33.3) | 20(60.6) | ||
Invasion | ||||
T1 (n=9) | 2(22.2) | 0.537 | 7(77.8) | 0.485 |
T2 (n=36) | 14(38.9) | 22(61.1) | ||
T3 (n=212) | 85(40.1) | 132(62.2) | ||
T4 (n=33) | 16(48.5) | 17(51.5) | ||
Lymph node metastasis | ||||
N0 (n=62) | 27(43.5) | 0.445 | 40(64.5) | 0.534 |
N1 (n=89) | 39(43.8) | 49(55.1) | ||
N2 (n=74) | 24(32.4) | 47(63.5) | ||
N3 (n=65) | 27(41.5) | 42(64.6) | ||
Survival | ||||
Survived (n=171) | 62(36.3) | 0.089 | 96(56.1) | 0.028 |
Died (n=119) | 55(46.2) | 82(68.9) |