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Table 2 NPP7 activity in the bile and the results of other clinical chemical analysis in patients in different groups

From: Changes of activity and isoforms of alkaline sphingomyelinase (nucleotide pyrophosphatase phosphodiesterase 7) in bile from patients undergoing endoscopic retrograde cholangiopancreatography

Group NPP7 nmol/h/ml NPP7 nmol/h/mg Bilirubin ALP GT n
Gallstone 311.6 ± 290.1 58.21 ± 69.93 54.59 ± 63.19 2.91 ± 1.60 6.69 ± 5.74 29
Tumor 164.9 ± 147.1* 25.16 ± 14.49* 161.2 ± 135.3** 12.2 ± 11.2** 14.15 ± 9.87* 13
PSC 184.4 ± 115.0 30.14 ± 26.97 56.67 ± 65.68 4.39 ± 3.00 5.06 ± 5.13 10
Others 312.6 ± 236.1 50.95 ± 31.09 124.9 ± 197.8 4.08 ± 3.52 4.75 ± 4.12 7
G + O 311.8 ± 277.3+ 56.89 ± 63.92+ 68.25 ± 103.4 3.14 ± 2.09 6.31 ± 5.47++ 36
T + PSC 173.2 ± 131.4* 27.33 ± 20.45* 118.5 ± 121.9* 9.19 ± 9.69** 10.44 ± 9.31 23
  1. The results are expressed as Mean ± SD. Statistical significance was determined by non-paired, two tails Mann–Whitney test. *P < 0.05, **P < 0.01 or less compared with gallstone group; + P < 0.05, ++ P < 0.01 or less, compared with tumor group. Significance was also found when gallstone + other benign diseases (G + O) was compared with tumour + PSC (T + PSC) for NPP7 and ALP, either per ml or per mg.