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Table 3 General characteristics of patients

From: Treatment with pirfenidone for two years decreases fibrosis, cytokine levels and enhances CB2 gene expression in patients with chronic hepatitis C

Characteristics

 

n= 34

Sex

Male, n (%)

13 (38%)

Female, n (%)

21 (62%)

Age at exposure (yr)

Mean ± SD

27 ± 9

Age at liver biopsy before treatment (yr)

Mean ± SD

56 ± 10

Age at liver biopsy after treatment (yr)

Mean ± SD

58 ± 10

Route of transmission

Blood transfusion, n (%)

29 (85%)

Nosocomial, n (%)

5 (15%)

Duration of HCV exposure (yr)

Mean ± SD

32 ± 10

HCV genotype

Genotype 1, n (%)

24 (70%)&

Genotype 2, n (%)

4 (12%)&

Genotype 3, n (%)

2 (6%)

ND, n (%)

5 (15%)

Change in HCV viral load after treatment

Increase 1 log, n (%)

1 (4%)

Unchanged*, n (%)

27 (96%)

Body mass index (Kg/m2)

Mean (±SD)

28 ± 7**

  1. &A patient presented co-infection with two genotypes of VHC. *Unchanged: modification less than 1 log in viral load; * *Overweight according to OMS; ND: not determined. HCV: Hepatitis C virus.