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Table 2 Secondary effects associated with pirfenidone treatment for two years

From: Treatment with pirfenidone for two years decreases fibrosis, cytokine levels and enhances CB2 gene expression in patients with chronic hepatitis C

Symptoms

*n = 28

%

**n = 34

%

Gastritis

17

81%

23

67%

Nausea

10

48%

12

35%

Rash

10

48%

10

29%

Photosensitivity

3

14%

3

9%

Headache

3

14%

4

12%

Vomiting

1

5%

1

3%

Dizziness

2

10%

2

6%

Weakness

2

10%

2

6%

Insomnia

1

5%

1

3%

Somnolence

1

5%

1

3%

  1. *Data in the 28 patients that conclude the study. Some patients presented more than one secondary effect.
  2. **The most common side secondary effect in the 34 enrolled patients including the 6 drop-out patients were gastritis, nausea and rash, these effects disappeared after 3 months of treatment.