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Table 2 Secondary effects associated with pirfenidone treatment for two years

From: Treatment with pirfenidone for two years decreases fibrosis, cytokine levels and enhances CB2 gene expression in patients with chronic hepatitis C

Symptoms *n = 28 % **n = 34 %
Gastritis 17 81% 23 67%
Nausea 10 48% 12 35%
Rash 10 48% 10 29%
Photosensitivity 3 14% 3 9%
Headache 3 14% 4 12%
Vomiting 1 5% 1 3%
Dizziness 2 10% 2 6%
Weakness 2 10% 2 6%
Insomnia 1 5% 1 3%
Somnolence 1 5% 1 3%
  1. *Data in the 28 patients that conclude the study. Some patients presented more than one secondary effect.
  2. **The most common side secondary effect in the 34 enrolled patients including the 6 drop-out patients were gastritis, nausea and rash, these effects disappeared after 3 months of treatment.