Risk score to predict gastrointestinal bleeding after acute ischemic stroke

BMC Gastroenterology

Table 2 Multivariable predictors of GIB after AIS from the derivation cohort (n = 8,820)

Variables	β-coefficients	adjusted O.R.*	95% C.I.	P value
Model intercept	-6.529
Age (years)	0.009	1.01	1.00-1.02	0.01
Gender (male)	0.370	1.45	1.13-1.85	0.004
Hypertension	0.345	1.41	1.10-1.82	0.008
Hepatic cirrhosis	1.299	3.66	1.17-11.5	<0.001
Peptic ulcer or previous GIB	1.226	3.41	2.28-5.10	<0.001
Pre-stroke dependence (mRS ≥3)	0.717	2.05	1.54-2.72	<0.001
Admission NIHSS (per 1 point increase)	0.063	1.07	1.04-1.09	<0.001
Admission GCS (per 1 point decrease)	0.057	1.06	1.01-1.11	0.01
OCSP subtype
Lacunar infarction (LACI)	…	1.00	…	…
Partial anterior circulation infarct (PACI)	0.169	1.18	0.80-1.75	0.39
Total anterior circulation infarct (TACI)	0.457	1.58	1.01-2.49	0.02
Posterior circulation infarct (POCI)	0.804	2.24	1.47-3.40	<0.001

*Multivariable logistic regression adjusted for age, gender, stroke risk factors, comorbidities, pre-stroke dependence, pre-admission antiplatelet therapy, pre-admission anticoagulation therapy, admission blood pressure, NIHSS score, GCS score, OCSP subtypes, intravenous t-PA, antithrombotic therapies within 48 h after admission, and length of hospital stay.
Abbreviation: GIB gastrointestinal bleeding, AIS acute ischemic stroke, OR odds ratio, C.I. confidence interval, mRS modified Rankin Scale, NIHSS National Institutes of Health Stroke Scale score, GCS Glasgow Coma Scale, OCSP Oxfordshire Community Stroke Project, t-PA tissue plasminogen activator.

ISSN: 1471-230X