Table 2 Characteristics of nocturnal acid breakthrough (NAB) monitored using intragastric pH monitoring following a single dose (20 mg) of rabeprazole, omeprazole and placebo in 18 obese volunteers. Values are medians and interquartiles (Q1-Q3)
NAB | Rabeprazole | Omeprazole | Placebo | p (OvsR) |
|---|---|---|---|---|
Number | 1 (1–2) | 2 (1–3) | 2 (1–3) | 0.04 |
Minimal pH | 0.7 (0.6-0.9) | 0.5 (0.3-0.8) | 0.4 (0.3-0.6) | 0.53 |
Median pH | 1.4 (1.2-1.5) | 1.3 (0.8-1.5) | 0.9 (0.7-1.1) | 0.47 |
Duration (h) | 5.1 (3.4-6.2) | 6.5 (4.6-8.9) | 9.2 (7.9-9.9) | 0.11 |