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Table 2 Characteristics of nocturnal acid breakthrough (NAB) monitored using intragastric pH monitoring following a single dose (20 mg) of rabeprazole, omeprazole and placebo in 18 obese volunteers. Values are medians and interquartiles (Q1-Q3)

From: Controlling on-demand gastric acidity in obese subjects: a randomized, controlled trial comparing a single dose of 20 mg rabeprazole and 20 mg omeprazole

NAB Rabeprazole Omeprazole Placebo p (OvsR)
Number 1 (1–2) 2 (1–3) 2 (1–3) 0.04
Minimal pH 0.7 (0.6-0.9) 0.5 (0.3-0.8) 0.4 (0.3-0.6) 0.53
Median pH 1.4 (1.2-1.5) 1.3 (0.8-1.5) 0.9 (0.7-1.1) 0.47
Duration (h) 5.1 (3.4-6.2) 6.5 (4.6-8.9) 9.2 (7.9-9.9) 0.11