Figure 2From: Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease Histopathology features of lymphomatoid granulomatosis in our case. A) H&E stain of liver core biopsy with a periportal polymorphous infiltrate composed of small lymphocytes, histiocytes, and plasma cells. B) EBV in situ hybridization (EBER) of liver showing no positively stained cells. C) H&E stain of lung wedge biopsy showing an extensive, focally angiocentric, polymorphic infiltrate with geographic tissue necrosis. D) EBER of lung showing scattered positive nuclear staining in the distribution of B-cells (CD20 immunostain not shown).Back to article page