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Table 3 Laboratory work-up of patients with HCC in NCL in comparison to patients with HCC in LC

From: Characterization and prognosis of patients with hepatocellular carcinoma (HCC) in the non-cirrhotic liver

Parameter (SI-units)

Patients with HCC in NCL

Patients with HCC in LC

p

 

n

Median

Range

n

Median

Range

 

Bilirubin

88

11.5

3.3-497.0

547

20.6

3.3-709.1

< 0.001

Quick

89

97.0

18-120

547

86.0

18-120

< 0.001

Albumin

81

40.10

15.6-71.0

507

36.1

9.5-72.5

< 0.001

ALAT

87

0.75

0.04-7.72

545

0.77

0.12-31.20

0.110

ASAT

86

0.76

0.17-12.11

546

1.11

0.26-25.90

< 0.001

GGT

80

2.43

0.19-36.28

518

3.26

0.17-66.51

0.002

Alcaline phosphatase

81

3.59

0.38-36.46

506

3.41

0.69-138.69

0.737

Creatinine

87

78.00

45-480

535

77.0

2-557

0.622

Urea nitrogen

83

5.8

2.1-44.2

513

5.9

1.6-35.8

0.437

Ferritin

32

452.5

21-2928

233

356.0

3-7585

0.553

Transferrin saturation

29

25.50

8.0-95.3

166

30.3

4.5-119.0

0.310

Coeruloplasmin

16

0.38

0.29-0.53

112

0.36

0.12-2.31

0.951

Hemoglobin

82

8.2

5.7-18.7

505

8.1

4.1-13.7

0.997

Platelets

81

261.0

84-693

506

166.5

33-799

< 0.001

PTT

84

28.5

22.1-60.0

527

31.5

19.2-80.2

< 0.001

IgA

15

2.56

0.61-22.80

101

5.42

1.27-43.30

< 0.001

IgM

13

0.970

0.5-2.6

96

1.19

0.2-15.5

0.274

IgG

14

13.05

8-28

103

16.30

2-46

0.117

CA 19-9

22

35.5

1.5-7520

226

60.00

<0.5-8483.0

0.057

AFP

85

32.10

1-378813.00

531

62.00

0.6-1460000.00

0.168

  1. ALAT = alanine aminotransferase, ASAT = aspartate aminotransferase, GGT = gamma glutamyl transferase, PPT = partial thromboplastin time, IgA = immunoglobulin A, IgG = immunoglobulin G, AFP = alpha fetoprotein, CA 19–9 = carbohydrate antigen 19–9.
  2. p-values indicating a statistical significance are printed in bold.