Clinical characteristics of elderly patients with proton pump inhibitor-refractory non-erosive reflux disease from the G-PRIDE study who responded to rikkunshito

Table 2 Patients background factors in the 2 groups

	RKT group	PL group	Pvalue
Mean age, years (range)	72.1 (65–85)	73.4 (65–83)	0.225^a
Gender, n, (M/F)	17/35	8/35	0.370^b
BMI (mean ± SD)	23.0 ± 3.6	22.9 ± 3.0	0.940^a
Current alcohol use, n (%)	7 (13.5)	3 (7.0)	0.517^b
Current smoking, n (%)	6 (11.5)	1 (2.3)	0.024^b
Helicobacter pylori infection, n (%)	13 (43.3)	5 (16.7)	0.115^b
Gastric mucosal atrophy, n (%)	37 (71.2)	27 (64.3)	0.096^b
Redness of gastric mucosa, n (%)	10 (19.2)	3 (7.1)	0.167^b
Impaired GEFV (grade III, IV), n (%)	16 (30.8)	9 (20.9)	0.427^b
Esophageal hiatal hernia (grade B and A), n (%)	23 (48.6)	17 (39.7)	0.413^b
Concomitant systemic diseases, n (%), (with)	34 (65.4)	26 (61.9)	0.785^b
Total FSSG score (mean ± SD)	16.0 ± 7.0	15.1 ± 6.4	0.457^c
Overall GSRS score (mean ± SD)	2.5 ± 0.9	2.3 ± 0.8	0.652^c

BMI, body mass index; GEFV, gastroesophageal flap valve; FSSG, Frequency Scale for the Symptoms of GERD; GSRS, Gastrointestinal Symptom Rating Scale.
^a, t-test; ^b, Fisher’s exact test; ^c, Wilcoxon’s signed rank test.

ISSN: 1471-230X