Table 4 Summarizing multifactor dimensionality reduction (MDR) models for gene-gene interaction in HCV treatment outcome
From: Association of MRC-1 and IL-28Bwith the treatment outcome of hepatitis C: a case control study
Number of factors | Best candidate models | Testing accuracy (%) | Pvalue* | Cross-validation consistency |
|---|---|---|---|---|
HCV-1 | ||||
1 | rs691005 | 64.3 | 0.01 | 10/10 |
2 | rs691005 rs8099917 | 62.7 | 0.001 | 6/10 |
3 | rs1926736 rs691005 rs8099917 | 61.3 | 0.01 | 6/10 |
4 | rs1926736 rs691005 rs8099917 rs10853728 | 61.2 | 0.01 | 7/10 |
HCV-2 | ||||
1 | rs10857328 | 58.8 | 0.2 | 6/10 |
2 | rs691005 rs8099917 | 70.01 | 0.06 | 10/10 |
3 | rs1926736 rs691005 rs8099917 | 58.9 | 0.6 | 9/10 |
4 | rs1926736 rs691005 rs8099917 rs10853728 | 49.2 | 0.96 | 10/10 |