Table 2 Typical GERD symptoms in the 5 classes (primary efficacy set N = 7434)
n (%) | Class 1 | Class 2 | Class 3 | Class 4 | Class 5 |
|---|---|---|---|---|---|
N = 1598 | N = 845 | N = 2375 | N = 1181 | N = 1435 | |
Heartburn | |||||
None | 53 (3.3) | 41 (4.9) | 12 (0.5) | 204 (17.3) | 0 |
Mild | 325 (20.3) | 310 (36.7) | 599 (25.2) | 369 (31.2) | 684 (47.7) |
Moderate | 913 (57.1) | 423 (50.1) | 1439 (60.6) | 544 (46.1) | 681 (47.5) |
Severe | 307 (19.2) | 71 (8.4) | 325 (13.7) | 64 (5.4) | 70 (4.9) |
Regurgitation | |||||
None | 107 (6.7) | 157 (18.6) | 199 (8.4) | 2 (0.2) | 1063 (74.1) |
Mild | 543 (34.0) | 356 (42.1) | 989 (41.6) | 650 (55.0) | 225 (15.7) |
Moderate | 757 (47.4) | 273 (32.3) | 1031 (43.4) | 465 (39.4) | 130 (9.1) |
Severe | 191 (12.0) | 59 (7.0) | 156 (6.6) | 64 (5.4) | 17 (1.2) |
Number of days per week | |||||
1 day per week | 70 (4.4) | 171 (20.2) | 131 (5.5) | 159 (13.5) | 258 (18.0) |
2 to 3 days per week | 529 (33.1) | 407 (48.2) | 823 (34.7) | 523 (44.3) | 631 (44.0) |
4 to 5 days per week | 546 (34.2) | 171 (20.2) | 804 (33.9) | 279 (23.6) | 309 (21.5) |
6 to 7 days per week | 453 (28.3) | 96 (11.4) | 617 (26.0) | 220 (18.6) | 237 (16.5) |
Time of occurrence | |||||
Only during the day | 405 (25.3) | 0 | 189 (8.0) | 1094 (92.6) | 1206 (84.0) |
Only during the night | 1 (0.1) | 845 (100) | 0 | 0 | 0 |
Both during day and night | 1192 (74.6) | 0 | 2186 (92.0) | 87 (7.4) | 229 (16.0) |