TY - JOUR AU - Prazak, Josef AU - Laszikova, Eva AU - Pantoflicek, Tomas AU - Ryska, Ondrej AU - Koblihova, Eva AU - Ryska, Miroslav PY - 2013 DA - 2013/06/08 TI - Cerebral microdialysis reflects the neuroprotective effect of fractionated plasma separation and adsorption in acute liver failure better and earlier than intracranial pressure: a controlled study in pigs JO - BMC Gastroenterology SP - 98 VL - 13 IS - 1 AB - Cerebral edema is a well-recognized and potentially fatal complication of acute liver failure (ALF). The effectiveness of treatments that address intracranial hypertension is generally assessed by measuring intracranial pressure (ICP). The aim of this study was to determine the role of cerebral microdialysis in monitoring the efficacy of fractionated plasma separation and adsorption (FPSA) treatment for ALF. We hypothesized that in ALF cerebral microdialysis reflects the benefits of FPSA treatment on cerebral edema before ICP. SN - 1471-230X UR - https://doi.org/10.1186/1471-230X-13-98 DO - 10.1186/1471-230X-13-98 ID - Prazak2013 ER -