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Table 4 Odds ratios and 95% CI according to predicted GST enzyme activity genotypes for ESCC and EAC patients compared to controls

From: No role for glutathione S-transferase genotypes in Caucasian esophageal squamous cell or adenocarcinoma etiology: an European case–control study

GST

Comparisons

ESCC OR (95%CI)*

EAC OR (95%CI)

GST M1

High- Intermediate

Ref

Ref

Low

1.06 (0.69 – 1.61)

0.94 (0.72 – 1.23)

GST A1

High

Ref

Ref

Intermediate

0.88 (0.56 – 1.38)

0.78 (0.58 – 1.06)

Low

0.58 (0.28 – 1.21)

0.91 (0.60 – 1.39)

GST P1

I105V

High

Ref

Ref

Intermediate

0.83 (0.53 – 1.29)

1.24 (0.93 – 1.67)

Low

0.92 (0.49 – 1.72)

1.01 (0.66 – (1.56)

GST P1

A114V

High

Ref

Ref

Intermediate

0.86 (0.47 – 1.59)

1.06 (0.73 – 1.54)

Low

 

1.11 (0.26 – 4.68)

GST T1

High-Intermediate

Ref

Ref

 

Low

0.80 (0.46 – 1.39)

1.15 (0.84 – 1.59)

  1. * Odds ratios were adjusted for gender.
  2. ESSC esophageal squamous cell carcinoma, EAC esophageal adenocarcinoma.