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Table 4 Odds ratios and 95% CI according to predicted GST enzyme activity genotypes for ESCC and EAC patients compared to controls

From: No role for glutathione S-transferase genotypes in Caucasian esophageal squamous cell or adenocarcinoma etiology: an European case–control study

GST Comparisons ESCC OR (95%CI)* EAC OR (95%CI)
GST M1 High- Intermediate Ref Ref
Low 1.06 (0.69 – 1.61) 0.94 (0.72 – 1.23)
GST A1 High Ref Ref
Intermediate 0.88 (0.56 – 1.38) 0.78 (0.58 – 1.06)
Low 0.58 (0.28 – 1.21) 0.91 (0.60 – 1.39)
GST P1
I105V
High Ref Ref
Intermediate 0.83 (0.53 – 1.29) 1.24 (0.93 – 1.67)
Low 0.92 (0.49 – 1.72) 1.01 (0.66 – (1.56)
GST P1
A114V
High Ref Ref
Intermediate 0.86 (0.47 – 1.59) 1.06 (0.73 – 1.54)
Low   1.11 (0.26 – 4.68)
GST T1 High-Intermediate Ref Ref
  Low 0.80 (0.46 – 1.39) 1.15 (0.84 – 1.59)
  1. * Odds ratios were adjusted for gender.
  2. ESSC esophageal squamous cell carcinoma, EAC esophageal adenocarcinoma.