| Placebo | Alfentanil | P value |
---|---|---|---|
Nausea | 2.2 (1/45) | 6.7 (3/45) | 0.62 |
Vomiting | 0.0 (0/45) | 2.2 (1/45) | 1.00 |
Dry mouth | 2.2 (1/45) | 0.0 (0/45) | 1.00 |
Blurry vision | 4.4 (2/45) | 2.2 (1/45) | 1.00 |
Dizziness | 4.4 (2/45) | 37.8 (17/45) | <0.001 |
Sleepy | 0.0 (0/45) | 2.2 (1/45) | 1.00 |
Dyspnoeic | 0.0 (0/45) | 2.2 (1/45) | 1.00 |
Sweating | 0.0 (0/45) | 2.2 (1/45) | 1.00 |
Pressure sensation | 0.0 (0/45) | 2.2 (1/45) | 1.00 |
Desaturation (SpO2 < 90%) * | 8.1 (3/37) | 44.4 (16/36) | <0.001 |
Desaturation >15 seconds (SpO2 < 90%) | 8.1 (3/37) | 19.4 (7/36) | 0.19 |
Desaturation (SpO2 < 85%) # | 2.7 (1/37) | 16.7 (6/36) | 0.06 |
Desaturation >15 seconds (SpO2 < 85%) # | 0.0 (0/37) | 0.0 (0/36) | 1.00 |
Irregular heart rhythm | 18.9 (7/37) | 16.7 (6/36) | 1.00 |
Systolic blood pressure at 5 minutes (20% decrease) | 8.9 (4/45) | 11.1 (5/45) | 1.00 |
Diastolic blood pressure at 5 minutes (20% decrease) | 20.0 (9/45) | 15.6 (7/45) | 0.78 |
Heart rate at 5 minutes (20% decrease) | 4.4 (2/45) | 0.0 (0/45) | 0.49 |