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Table 3 Side effects

From: A multi-centre randomised double-blind placebo-controlled trial to evaluate the value of a single bolus intravenous alfentanil in CT colonography

  Placebo Alfentanil P value
Nausea 2.2 (1/45) 6.7 (3/45) 0.62
Vomiting 0.0 (0/45) 2.2 (1/45) 1.00
Dry mouth 2.2 (1/45) 0.0 (0/45) 1.00
Blurry vision 4.4 (2/45) 2.2 (1/45) 1.00
Dizziness 4.4 (2/45) 37.8 (17/45) <0.001
Sleepy 0.0 (0/45) 2.2 (1/45) 1.00
Dyspnoeic 0.0 (0/45) 2.2 (1/45) 1.00
Sweating 0.0 (0/45) 2.2 (1/45) 1.00
Pressure sensation 0.0 (0/45) 2.2 (1/45) 1.00
Desaturation (SpO2 < 90%) * 8.1 (3/37) 44.4 (16/36) <0.001
Desaturation >15 seconds (SpO2 < 90%) 8.1 (3/37) 19.4 (7/36) 0.19
Desaturation (SpO2 < 85%) # 2.7 (1/37) 16.7 (6/36) 0.06
Desaturation >15 seconds (SpO2 < 85%) # 0.0 (0/37) 0.0 (0/36) 1.00
Irregular heart rhythm 18.9 (7/37) 16.7 (6/36) 1.00
Systolic blood pressure at 5 minutes (20% decrease) 8.9 (4/45) 11.1 (5/45) 1.00
Diastolic blood pressure at 5 minutes (20% decrease) 20.0 (9/45) 15.6 (7/45) 0.78
Heart rate at 5 minutes (20% decrease) 4.4 (2/45) 0.0 (0/45) 0.49
  1. This table shows the percentage of patients with different side effects for the placebo and alfentanil group.
  2. * All > 15 sec and < 85% desaturations are also counted for this category.
  3. # All < 85% saturations lasted 2–9 seconds, on average 4.2 seconds.