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Table 3 Side effects

From: A multi-centre randomised double-blind placebo-controlled trial to evaluate the value of a single bolus intravenous alfentanil in CT colonography

 

Placebo

Alfentanil

P value

Nausea

2.2 (1/45)

6.7 (3/45)

0.62

Vomiting

0.0 (0/45)

2.2 (1/45)

1.00

Dry mouth

2.2 (1/45)

0.0 (0/45)

1.00

Blurry vision

4.4 (2/45)

2.2 (1/45)

1.00

Dizziness

4.4 (2/45)

37.8 (17/45)

<0.001

Sleepy

0.0 (0/45)

2.2 (1/45)

1.00

Dyspnoeic

0.0 (0/45)

2.2 (1/45)

1.00

Sweating

0.0 (0/45)

2.2 (1/45)

1.00

Pressure sensation

0.0 (0/45)

2.2 (1/45)

1.00

Desaturation (SpO2 < 90%) *

8.1 (3/37)

44.4 (16/36)

<0.001

Desaturation >15 seconds (SpO2 < 90%)

8.1 (3/37)

19.4 (7/36)

0.19

Desaturation (SpO2 < 85%) #

2.7 (1/37)

16.7 (6/36)

0.06

Desaturation >15 seconds (SpO2 < 85%) #

0.0 (0/37)

0.0 (0/36)

1.00

Irregular heart rhythm

18.9 (7/37)

16.7 (6/36)

1.00

Systolic blood pressure at 5 minutes (20% decrease)

8.9 (4/45)

11.1 (5/45)

1.00

Diastolic blood pressure at 5 minutes (20% decrease)

20.0 (9/45)

15.6 (7/45)

0.78

Heart rate at 5 minutes (20% decrease)

4.4 (2/45)

0.0 (0/45)

0.49

  1. This table shows the percentage of patients with different side effects for the placebo and alfentanil group.
  2. * All > 15 sec and < 85% desaturations are also counted for this category.
  3. # All < 85% saturations lasted 2–9 seconds, on average 4.2 seconds.