Category | Total (n=191) | Diabetic (n=84) | Non-Diabetic (n=107) | P Value |
---|---|---|---|---|
Age (Mean ± StDev) | 57.2 ± 8.6 | 60.7 ± 7.2 | 55.03 ± 8.9 | < 0.0001 |
>65 years old (%) | 40 (20.9%) | 24 (28.6%) | 16 (15.0%) | 0.022 |
Sex (% Male) | 164 (85.9%) | 75 (89.3 %) | 89 (83.2 %) | 0.23 |
Body mass index > 30 | 78 (40.8%) | 40 (47.6%) | 42 (39.3%) | 0.017 |
Etiologic Risk Factors * | ||||
Alcohol abuse | 47 (24.6%) | 18 (21.4%) | 29 (27.1%) | 0.37 |
Hepatitis C | 104 (54.5%) | 37 (44%) | 67 (62.6%) | 0.011 |
Hepatitis B | 12 (6.2%) | 5 (5.9%) | 7 (6.5%) | 0.86 |
Non-alcoholic steatohepatitis | 14 (7.3%) | 11 (13.1%) | 3 (2.8%) | 0.007 |
Cryptogenic | 20 (10.5%) | 13 (15.5%) | 7 (6.5%) | 0.057 |
Tumor Characteristics | ||||
Total tumor diameter (mean)+ | 5.42 | 5.81 | 5.125 | 0.29 |
Multinodular | 107 (56%) | 46 (54.8%) | 61 (57%) | 0.77 |
Macrovascular Invasion | 27 (14.1%) | 17 (20.2%) | 10 (9.3%) | 0.032 |
Microvascular Invasion Only | 33(17.4%) | 15 (17.9%) | 18 (17.0%) | 0.87 |
Portal Vein Thrombosis | 33 (17.3%) | 19 (22.6%) | 14 (13.1%) | 0.12 |
Laboratory Parameters++ | ||||
MELD score (Mean ± SD) | 15.91 ± 7.8 | 14.69 ± 7.19 | 16.86 ± 8.27 | 0.062 |
INR (Mean ± SD) | 1.51 ± 0.52 | 1.37 ± 0.35 | 1.64 ± 0.59 | 0.001 |
Albumin (Mean ± SD) | 3.3 ± 0.73 | 3.34 ± 0.82 | 3.27 ± 0.65 | 0.55 |
Bilirubin (Mean ± SD) | 4.12 ± 5.69 | 3.34 ± 4.96 | 4.73 ± 6.16 | 0.071 |
Creatinine (Mean ± SD) | 1.27 ± 0.81 | 1.36 ± 0.94 | 1.21 ± 0.70 | 0.20 |
Alpha fetoprotein IU/ml (median) | 16.5+++ | 16.5 | 16.5 | 0.63 |
Alpha fetoprotein IU/ml (mean) | 978 | 542 | 0.35 | |
HCC treatment | ||||
Chemoembolization | 5(2.6%) | 3(3.6%) | 2 (1.9%) | 0.76 |
Radiation | 11(5.8%) | 4 (4.8%) | 7 (6.5%) | 0.76 |
Ablation | 7 (3.7%) | 3 (3.6%) | 4 (3.7%) | 0.95 |
Transplant wait list time (mean number of months) | 5.9 months | 7.5 months | 0.43 |