Skip to main content

Table 1 Patient characteristics

From: Diabetes mellitus impacts risk of macrovascular invasion in patients undergoing transplantation for hepatocellular carcinoma

Category

Total (n=191)

Diabetic (n=84)

Non-Diabetic (n=107)

P Value

Age (Mean ± StDev)

57.2 ± 8.6

60.7 ± 7.2

55.03 ± 8.9

< 0.0001

>65 years old (%)

40 (20.9%)

24 (28.6%)

16 (15.0%)

0.022

Sex (% Male)

164 (85.9%)

75 (89.3 %)

89 (83.2 %)

0.23

Body mass index > 30

78 (40.8%)

40 (47.6%)

42 (39.3%)

0.017

Etiologic Risk Factors *

    

Alcohol abuse

47 (24.6%)

18 (21.4%)

29 (27.1%)

0.37

Hepatitis C

104 (54.5%)

37 (44%)

67 (62.6%)

0.011

Hepatitis B

12 (6.2%)

5 (5.9%)

7 (6.5%)

0.86

Non-alcoholic steatohepatitis

14 (7.3%)

11 (13.1%)

3 (2.8%)

0.007

Cryptogenic

20 (10.5%)

13 (15.5%)

7 (6.5%)

0.057

Tumor Characteristics

    

Total tumor diameter (mean)+

5.42

5.81

5.125

0.29

Multinodular

107 (56%)

46 (54.8%)

61 (57%)

0.77

Macrovascular Invasion

27 (14.1%)

17 (20.2%)

10 (9.3%)

0.032

Microvascular Invasion Only

33(17.4%)

15 (17.9%)

18 (17.0%)

0.87

Portal Vein Thrombosis

33 (17.3%)

19 (22.6%)

14 (13.1%)

0.12

Laboratory Parameters++

    

MELD score (Mean ± SD)

15.91 ± 7.8

14.69 ± 7.19

16.86 ± 8.27

0.062

INR (Mean ± SD)

1.51 ± 0.52

1.37 ± 0.35

1.64 ± 0.59

0.001

Albumin (Mean ± SD)

3.3 ± 0.73

3.34 ± 0.82

3.27 ± 0.65

0.55

Bilirubin (Mean ± SD)

4.12 ± 5.69

3.34 ± 4.96

4.73 ± 6.16

0.071

Creatinine (Mean ± SD)

1.27 ± 0.81

1.36 ± 0.94

1.21 ± 0.70

0.20

Alpha fetoprotein IU/ml (median)

16.5+++

16.5

16.5

0.63

Alpha fetoprotein IU/ml (mean)

 

978

542

0.35

HCC treatment

    

Chemoembolization

5(2.6%)

3(3.6%)

2 (1.9%)

0.76

Radiation

11(5.8%)

4 (4.8%)

7 (6.5%)

0.76

Ablation

7 (3.7%)

3 (3.6%)

4 (3.7%)

0.95

Transplant wait list time (mean number of months)

 

5.9 months

7.5 months

0.43

  1. * Five patients had more than one etiologic risk factor.
  2. + seven missing values.
  3. ++twenty one patients from pre-MELD era were missing laboratory values and MELD score.
  4. +++ two missing values.