Figure 4

Effect of corilagin on NF-κBp65 expression at 48h. The activated NF-κBp65 presented brown stain in nuclear and inactivated NF-κBp65 presented brown in cytoplasm. A: Corilagin group; B: UDCA group; C: Dexamethasone group. D: Model group; E: Normal group. It was shown that in normal group the staining of NF-κBp65 in nucleus was not remarkable. After ANIT administration, the positive rate of NF-κBp65 staining in nucleus significantly rose (P<0.01). With corilagin treatment, the rate of NF-κBp65 staining in nucleus was decreased markedly (P<0.01). In UDCA and dexamethasone group the rate was also significantly lower than that in model group but higher than that in corilagin group (P<0.05).