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Figure 5 | BMC Gastroenterology

Figure 5

From: Age-of-onset-dependent influence of NOD2 gene variants on disease behaviour and treatment in Crohn’s disease

Figure 5

Effect of NOD2 variant alleles on treatment in pediatric- and adult-onset CD. CD patients with pediatric-onset (A) or adult-onset (B) of disease with NOD2 variant (grey bars) or NOD2 wild-type alleles (white bars) are compared regarding steroid-dependent or refractory course of disease, need for long-term immunosuppressive therapy with azathioprine (AZA) and methotrexate (MTX) or anti-TNFα antibody. Differences were compared using chi-square or Fishers exact test, respectively. A p-value below ≤0.05 was considered to be significant.

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