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Table 2 Comparison of non-amino acid metabolite levels between the control and ALF groups

From: Metabonomic analysis of liver tissue from BALB/c mice with d-galactosamine/lipopolysaccharide-induced acute hepatic failure

No.

Retention Time

Metabolites

Control Group

ALF Group

Ratioa

P

16

6.02

lactate

238.84 ± 36.26

233.85 ± 38.91

0.98

0.8318

17

7.88

ethanedioic acid

5.92 ± 2.28

4.06 ± 1.51

0.69

0.1749

18

8.39

β-hydroxybutyrate

17.43 ± 1.96

5.09 ± 1.95

0.29

0.0017

19

10.91

urea

43.17 ± 6.07

20.54 ± 2.04

0.48

0.0013

20

11.20

phosphate

61.90 ± 10.34

38.67 ± 8.61

0.62

0.0279

21

11.30

glycerol

502.25 ± 42.61

459.58 ± 41.69

0.92

0.1886

22

12.35

succinic acid

30.58 ± 2.72

3.76 ± 1.68

0.12

0.0000

23

12.90

uracil

26.65 ± 5.82

29.78 ± 8.73

1.12

0.6393

24

13.31

fumaric acid

12.96 ± 3.60

11.67 ± 4.08

0.90

0.6120

25

13.78

pyruvate acid

8.46 ± 1.62

8.75 ± 0.96

1.03

0.7939

26

16.76

malic acid

45.24 ± 8.33

48.72 ± 4.17

1.08

0.4257

27

17.70

4-amino-butanoic acid

29.14 ± 3.50

33.28 ± 9.01

1.14

0.4762

28

18.50

erythronic acid

3.06 ± 0.77

1.01 ± 0.32

0.33

0.0064

29

19.28

2-piperidinedicarboxylic acid

19.73 ± 6.01

13.73 ± 5.56

0.70

0.0985

30

21.20

2,3,4-trihydroxy-butanal

99.30 ± 10.48

52.41 ± 12.11

0.53

0.0021

31

23.07

phosphoglyceride

114.73 ± 29.17

31.67 ± 9.72

0.28

0.0014

32

23.43

2-(bisamino)ethyl-phosphoric acid

48.32 ± 7.80

44.76 ± 9.20

0.93

0.3720

33

23.86

hypoxanthine

96.71 ± 15.64

62.57 ± 7.83

0.65

0.0425

34

24.26

arabinonic acid

1.66 ± 0.59

36.94 ± 5.53

22.25

0.0003

35

24.90

tetradecoic acid

74.92 ± 7.62

49.23 ± 8.42

0.66

0.0058

36

25.33

fructose

5.97 ± 1.30

3.19 ± 0.85

0.53

0.0092

37

25.63

glucose

439.00 ± 67.12

360.72 ± 42.74

0.82

0.0450

38

25.72

mannose

64.66 ± 14.56

37.53 ± 12.48

0.58

0.0137

39

26.22

galactose

158.06 ± 41.44

123.44 ± 19.37

0.78

0.0703

40

27.13

gluconic acid

66.74 ± 12.23

11.59 ± 4.73

0.17

0.0002

41

27.55

glucopyranose

98.84 ± 37.07

73.62 ± 27.60

0.74

0.3248

42

27.69

pantothenic acid

2.61 ± 1.12

2.47 ± 1.36

0.95

0.8489

43

28.18

purine

72.29 ± 18.01

35.07 ± 5.22

0.49

0.0180

44

28.48

6-deoxy-mannose

28.08 ± 7.66

10.19 ± 2.39

0.36

0.0052

45

28.84

palmitic acid

154.73 ± 16.61

162.99 ± 6.64

1.05

0.4927

46

29.54

inositol

85.87 ± 1.51

83.94 ± 6.01

0.98

0.5510

47

30.44

sedoheptulose

20.10 ± 7.80

3.07 ± 1.40

0.15

0.0121

48

31.82

linoleic acid

155.45 ± 17.62

144.69 ± 10.84

0.93

0.3358

49

31.93

oleic acid

116.51 ± 15.37

105.46 ± 7.70

0.91

0.3304

50

32.40

stearic acid

79.60 ± 5.93

83.70 ± 2.35

1.05

0.2288

51

33.63

glucopyranose phosphate

4.34 ± 1.76

2.36 ± 0.77

0.54

0.0538

52

32.44

arachidonic acid

62.30 ± 9.64

41.11 ± 8.21

0.66

0.0103

53

35.07

inositol monophosphate

5.50 ± 0.76

2.66 ± 0.70

0.48

0.0030

54

37.31

fructose phosphate

13.23 ± 4.61

0.50 ± 0.20

0.04

0.0061

55

37.44

ducosahexenoic acid

37.45 ± 5.03

37.42 ± 14.06

1.00

0.9963

56

37.70

adenosine

197.33 ± 36.90

29.66 ± 9.87

0.15

0.0008

57

40.15

maltose

41.62 ± 11.28

80.62 ± 27.90

1.94

0.0390

58

45.60

cholesterol

66.99 ± 11.90

35.54 ± 8.76

0.53

0.0330

  1. aMeans ratio of metabolite levels between ALF and control groups.