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Table 1 Comparison of liver amino acid levels between the control and ALF groups

From: Metabonomic analysis of liver tissue from BALB/c mice with d-galactosamine/lipopolysaccharide-induced acute hepatic failure

No. Retention Time Amino Acids Control Group ALF Group Ratioc P
1 6.98 alanine 197.63 ± 25.91 162.54 ± 23.76 0.82 0.0889
2 9.87 valine 81.52 ± 9.32 79.34 ± 13.53 0.97 0.8230
3 11.78 isoleucine 41.67 ± 8.16 43.00 ± 5.56 1.03 0.8026
4 11.86 5-oxy-proline 44.91 ± 11.28 50.17 ± 6.79 1.12 0.5499
5 12.10 glycine 157.18 ± 18.62 120.83 ± 11.80 0.77 0.0208
6 13.53 serine 98.42 ± 7.32 100.49 ± 9.06 1.02 0.7926
7 14.15 threonine 88.84 ± 10.42 77.97 ± 7.22 0.88 0.1624
8 15.20 B-alanine 38.87 ± 9.79 19.36 ± 1.63 0.50 0.0182
9 17.43 proline 99.95 ± 17.81 74.37 ± 7.51 0.74 0.0472
10 17.53 aspartate 54.20 ± 11.68 50.40 ± 4.85 0.93 0.6024
11 19.90 glutamate 98.41 ± 15.86 77.18 ± 5.01 0.78 0.0491
12 20.98 asparagine 2.06 ± 0.81 2.60 ± 0.78 1.26 0.5246
13 24.18 ornithine 41.78 ± 10.86 67.31 ± 14.79 1.61 0.1087
14 25.57 tyrosine 67.81 ± 9.84 32.34 ± 9.02 0.48 0.0008
15 26.37 lysine 10.61 ± 1.61 64.29 ± 12.27 6.06 0.0008
   TAAa 1123.87 ± 115.19 1022.21 ± 113.20 0.91 0.2207
   Gluconeogenic amino acidsb 1003.66 ± 118.93 858.26 ± 85.36 0.86 0.0656
  1. a Total amino acids. bGluconeogenic amino acids include aspartate, serine, glycine, threonine, alanine, proline, lysine, tyrosine, valine, and isoleucine. cMeans ratio of metabolite levels between ALF and control groups.