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Table 1 Quantiative pathological findings in relation to the time course

From: Different healing process of esophageal large mucosal defects by endoscopic mucosal dissection between with and without steroid injection in an animal model

 

Steroid injection

Steroid injection

(−)

(+)

Immediately after

1 week after

3 weeks after

8 weeks after

ESD

ESD

ESD

ESD

(n=5)

(n=7)

(n=2)

(n=5)

Ulcer size evaluated as distance between desmin-positive muscularis mucosa edges (cm, mean±SD)

1.38±0.22

1.54±0.23

0.80±0.14

0.78±0.11

Largest thickness of SMA-positive myofibroblastic cell bundles (μm, mean±SD)

0*

297±70.5

1,156±283

341±216

Thickness of proper muscle layer (μm, mean±SD)

1,231±112

1,444±123

584±218

NA**

  1. SMA: α-smooth muscle actin; SD: standard deviation; NA: not applicable.
  2. “n” means the number of preparations that were made from the esophagus of each pig.
  3. *no SMA-positive myofibroblastic cells identified.
  4. **The muscular layer was disrupted, which made the measurement difficult.