| |
Steroid injection
|
Steroid injection
|
|---|
|
(−)
|
(+)
|
|---|
|
Immediately after
|
1 week after
|
3 weeks after
|
8 weeks after
|
|---|
|
ESD
|
ESD
|
ESD
|
ESD
|
|---|
|
(n=5)
|
(n=7)
|
(n=2)
|
(n=5)
|
|---|
|
Ulcer size evaluated as distance between desmin-positive muscularis mucosa edges (cm, mean±SD)
|
1.38±0.22
|
1.54±0.23
|
0.80±0.14
|
0.78±0.11
|
|
Largest thickness of SMA-positive myofibroblastic cell bundles (μm, mean±SD)
|
0*
|
297±70.5
|
1,156±283
|
341±216
|
|
Thickness of proper muscle layer (μm, mean±SD)
|
1,231±112
|
1,444±123
|
584±218
|
NA**
|
- SMA: α-smooth muscle actin; SD: standard deviation; NA: not applicable.
- “n” means the number of preparations that were made from the esophagus of each pig.
- *no SMA-positive myofibroblastic cells identified.
- **The muscular layer was disrupted, which made the measurement difficult.
