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Table 2 Comparison of various methods for diagnosing H. pylori infection in children with gastritis, using gold standard (GS) or mucosal florescent quantitative PCR (mfqPCR) as the reference

From: Evaluation of a new fluorescence quantitative PCR test for diagnosing Helicobacter pylori infection in children

 

Routine histology

RUT

13C-UBT

Gastric fluid PCR

Dental plaque PCR

Standard

GS

mfqPCR

GS

mfqPCR

GS

mfqPCR

GS

mfqPCR

GS

mfqPCR

Sensitivity %

92.1

76.1

92.1

76.1

81.6

60.9

84.2

69.6

78.9

65.2

Specificity %

100.0

100.0

90.0

89.1

97.0

96.7

100.0

100.0

100.0

100.0

PPV %

100.0

100.0

77.8

77. 8

90.3

90.3

100.0

100.0

100.0

100.0

NPV %

97.1

89.3

96.8

88.2

90.1

83.2

94.3

86.8

92.6

85.2

  1. PPV: positive predictive value; NPV: negative predictive value; RUT: rapid urease test; 13C-UBT, urea breath test.