Figure 5

Plasma IL-6 abundance post ischemia-reperfusion or sham laparotomy in remifentanil-pretreated and saline control mice. Blood was obtained immediately after the 60 min period of reperfusion and IL-6 was assayed by ELISA. Open bars, saline pretreatment; filled bars, remifentanil pretreatment. Bars show absolute cytokine concentrations (means ± s.e.m.) in the sham (Sham) and ischemia-reperfusion (IR) groups; *, P < 0.05 for saline vs remifentanil; ##, P < 0.01 for Sham (combined treatment groups) vs IR. n = 4 for both saline groups and the remifentanil/Sham group, n = 5 for the remifentanil/IR group.