Variable | Mebeverine | Methylcellulose | Placebo | Significance |
---|---|---|---|---|
IBS-SSS total mean (n = 123) | 203.1(181.3- 223.0) | 205.4 (185.3 -225.5) | 210.9 (191.1 - 230.7) | p = 0.865 |
IBS-QOL score (n = 123) | 68.9 (64.1 – 73.6) | 66.3 (61.9 – 70.8) | 70.2 (65.9 – 74.6) | P = 0.453 |
HADS score for anxiety (n = 114) | 8.2 (7.3 – 9.1) | 8.7 (7.9- 9.6) | 9.0 (8.2 -9.8) | p = 0.422 |
HADS score for depression (n = 114) (%) |  |  |  | P = 0.655 |
Normal (0–7) | 25 (78.1) | 35 (89.7) | 33 (76.7) |  |
Mild (8–10) | 5 (15.6) | 2 (5.1) | 7 (16.3) |  |
Moderate or Severe (11–21) | 2 (6.3) | 2 (5.1) | 3 (7.0) |  |
Enablement score (n = 113) |  |  |  | P = 0.231 |
0 | 6 (19.4) | 14 (35.9) | 12 (27.9) | Â |
1-2 | 5 (16.1) | 6 (15.4) | 5 (11.6) | Â |
3-5 | 9 (29.0) | 11 (28.2) | 15 (34.9) | Â |
6-12 | 11 (35.5) | 8 (20.5) | 11(25.6) | Â |
SGA (%) | Â | Â | Â | Â |
Responders | 16 (57.1) | 17 (43.6) | 19 (44.2) | P = 0.538 |
Non responders | 12 (42.9) | 22 (56.4) | 24 (55.8) | Â |