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Table 1 Patient’s general characteristics and laboratory parameter by outcome

From: Serum sodium based modification of the MELD does not improve prediction of outcome in acute liver failure

 

Reference ranges

Spontaneously recovered (SR) (n=65)

Not spontaneously recovered (NSR) (n=43)

Transplanted ( LTx) (n=24)

Deceased (†) (n=19)

SR vs. NSR

SR vs. †

SR vs. LTx

LTx vs. †

Gender female (%)

 

38 (58%)

31 (72%)

17 (71%)

14 (73%)

 

Age**

 

41 (64)

49 (61)

41.5 (48)

56 (54)

p<0.05

p<0.05

n.s.

p<0.05

BMI (kg/m 2 ) **

 

23.37 (30.59)

26.64 (46.83)

25.91 (28.54)

27.7 (42.82)

n.s.

n.s.

n.s.

n.s.

PLATELETS [/nl]**

140-380

181 (350)

165 (450)

176.5 (450)

130 (325)

n.s.

n.s.

n.s.

n.s.

GGT [U/l]**

<55

113 (1102)

154 (1938)

154 (720)

158 (1938)

n.s.

n.s.

n.s.

n.s.

ALP [U/l]**

25-124

151 (3024)

183 (670)

173 (450)

214 (571)

n.s.

p<0.05

n.s.

n.s.

AST [U/l]**

<50

2329 (18650)

1081 (15388)

837 (4642)

2342 (15388)

n.s.

n.s.

p<0.05

n.s.

ALT [U/l]**

<50

2288 (12955)

1092 (7954)

946.5 (7177)

1682 (7835)

p<0.05

n.s.

p<0.05

n.s.

INR**

0.89-1.11

1.77 (2.96)

3.35 (8.36)

3.64 (7.88)

2.88 (8.17)

p<0.05.

p<0.05

p<0.05

n.s.

Direct bilirubin [mg/dl]**

<0.2

5.8 (28.7)

13.8 (30)

18.25 (28)

9.3 (24.4)

p<0.05

n.s.

p<0.05

p<0.05

Total bilirubin [mg/dl]**

0.3-1.2

11.4 (40.5)

20.2 (43.1)

21.85 (37.7)

15.4 (38.9)

p<0.05

n.s.

p<0.05

p<0.05

Creatinine [mg/dl]**

0.6-1.3

0.99 (5.09)

1.81 (4.43)

1.385 (4.43)

2.5 (3.87)

p<0.05

p<0.05

p<0.05

p<0.05

Sodium [mmol/l]**

136-145

138 (24)

138 (27)

137.5 (23)

139 (27)

n.s.

n.s.

p<0.05

n.s.

MELD*

 

23.55 ± 0.66

36.37 ± 0.68

36.33 ± 0.8638

36.42 ± 1.12

p<0.05

p<0.05

p<0.05

n.s.

UKELD*

 

58.39 ± 0.57

65.12 ± 0.73

66.29 ± 0.8666

63.47 ± 1.20

p<0.05

p<0.05

p<0.05

n.s.

MELD-Na*

 

24.5 ± 0.65

36.49 ± 0.65

36.67 ± 0.81

36.24 ± 1.1

p<0.05

p<0.05

p<0.05

n.s.

  1. *Mean ± Standard Error; *p<0.05 (Student’s t-Test for unrelated groups; SPSS software, version).**Median (Range); **p<0.05 (Mann- Whitney- U- Test; SPSS software).