Table 1 Baseline characteristics of patients (full analysis set)
Variable | Esomeprazole 20 mg once daily (n=130) |
|---|---|
Women | 95 (73.1) |
Age | |
Mean±SD (range), years | 62.1±12.6 (32–84) |
≤64 years | 63 (48.5) |
≥65 to ≤74 years | 43 (33.1) |
≥75 years | 24 (18.5) |
Type of arthritic disease | |
Rheumatoid arthritis | 42 (32.3) |
Osteoarthritis | 34 (26.2) |
Other chronic condition | 54 (41.5) |
Duration of disease, mean±SD (range), years | 6.0±6.9 (0–38) |
Helicobacter pylori infection (serology test) | 57 (43.8) |
Use of corticosteroids | 32 (24.6) |
CYP2C19 genotype | |
Poor metaboliser | 22 (16.9) |
Hetero extensive metaboliser | 68 (52.3) |
Homo extensive metaboliser | 40 (30.8) |