Characteristic | RR negative (n=300) | RR positive (n=15) | P-value |
---|---|---|---|
Demographics | Â | Â | Â |
 Median age, yrs | 51 (44–54) | 51 (46–61) | 0.38 |
 Male gender | 61% (182) | 73% (11) | 0.42 |
HCV genotype 1 | 76% (228) | 73% (11) | 0.76 |
Prior injection drug use | 45% (134) | 47% (7) | 1.00 |
Prior HCV treatment | 3% (9) | 33% (5) | <0.0005 |
Biochemical data †|  |  |  |
 ALT, IU/L | 65 (42–110) | 52 (24–80) | 0.16 |
 Platelets, x109/L | 202 (167–243) | 182 (134–245) | 0.38 |
Histologic characteristics | Â | Â | Â |
 A2-3 necroinflammation | 73% (218) | 53% (8) | 0.14 |
 F2-4 fibrosis | 66% (198) | 67% (10) | 1.00 |
Autoantibodies | Â | Â | Â |
 ANA positive | 89% (266) | 100% (15) | 0.39 |
 AMA positive | 2% (5) | 0% (0) | 1.00 |