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Table 4 Presence of symptoms, classification of celiac serology and Marsh grading of biopsy histology before and after treatment with Gluten Contamination Elimination Diet

From: Trace gluten contamination may play a role in mucosal and clinical recovery in a subgroup of diet-adherent non-responsive celiac disease patients

Symptoms

Pre-Diet: n (%)

Post-Diet: n (%)

Asymptomatic

1 (6%)

14 (82%)

Symptomatic

16 (94%)

3 (18%)

Histology

Pre-Diet: n (%)

Post-Diet: n (%)

Biopsy obtained

12 (71%)

5 (29%)

 Marsh 3

 7

 1

 Marsh 2

 2

 

 Marsh 0-1

 3

 4

Celiac Serology 1

Pre-Diet: n (%)

Post-Diet: n (%)

High celiac serology

10 (59%)

2 (12%)

Weak positive celiac serology

3 (18%)

5 (30%)

Negative celiac serology

4 (24%)

10 (59%)

  1. 1 Celiac serology defined as negative, weak positive or high using the cut-offs provided by the ELISA kit manufacturer. Tissue transglutaminase (tTG) IgA was followed in 16/17 patients; anti-endomysial (EMA) IgA was followed in the remaining patient.