Genetic polymorphisms of epidermal growth factor in relation to risk of hepatocellular carcinoma: two case-control studies

Table 2 The genotypic and allelic frequencies of the EGF polymorphism among control subjects by race/ethnicity

Genetic polymorphism	Non-Asians in Los Angeles, California		Chinese in southern Guangxi, China
Genetic polymorphism	Non-Hispanic whites (n = 179)	Blacks/Hispanics (n = 46)	Han Chinese (n = 196)	Zhuang/Yao Chinese (n = 49)
*EGF 61A > G*
A/A	0.21	0.50	0.48	0.49
A/G	0.48	0.33	0.43	0.45
G/G	0.31	0.17	0.09	0.06
A	0.45	0.66	0.70	0.71
G	0.55	0.34	0.30	0.29
2-sided P for HW†	0.81	0.07	0.72	0.48
2-sided P‡	0.0003		0.84

* Test for differences in genotypic frequencies between the four racial/ethnic groups.
† Test for the Hardy-Weinberg linkage equilibrium within each racial/ethnic group.
‡ Test for differences in genotypic frequencies between the two racial/ethnic groups within a given study location.

ISSN: 1471-230X