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Table 2 Anthropometric and metabolic characteristics of the Stuttgart study cohort

From: Role of the ABCG8 19H risk allele in cholesterol absorption and gallstone disease

  Total Normal weight Overweight
Parameter Controls Gallstone carriers Controls Gallstone carriers Controls Gallstone carriers
Number 134 34 75 11 59 23
Age (years) 57 ± 1.1 61 ± 1.9 55 ± 1.5 63 ± 3.6 59 ± 1.4 60 ± 2.3
BMI (kg/m2) 25.2 ± 0.3 26.6 ± 0.6 α 22.7 ± 0.3 23.3 ± 0.6 28.4 ± 0.4 28.2 ± 0.6
Total cholesterol (mg/dL) 214 ± 3.7 207 ± 6.2 211 ± 4.7 214 ± 6.3 217 ± 6.0 203 ± 8.8
Total triglycerides (mg/dL) 121 ± 6.1 126 ± 7.8 101 ± 6.8 125 ± 14.2 143 ± 9.9 127 ± 9.5
Lathosterol:Cholesterol (μg/mg) 1.15 ± 0.06 1.33 ± 0.15η 0.99 ± 0.07 1.22 ± 0.26 1.33 ± 0.09δ 1.39 ± 0.18
Sitosterol:Cholesterol (μg/mg) 1.23 ± 0.06 0.97 ± 0.08 β 1.36 ± 0.09 1.11 ± 0.19 1.06 ± 0.07ε 0.90 ± 0.06
Campesterol:Cholesterol (μg/mg) 1.47 ± 0.07 1.16 ± 0.11 γ 1.67 ± 0.12 1.23 ± 0.24 1.24 ± 0.08ζ 1.12 ± 0.11
  1. BMI = body mass index.
  2. Values are given as means ± SEM (standard error of the mean).
  3. Significance between the controls and gallstone carriers was analysed with Mann–Whitney U-test (nonparametric, two-tailed).
  4. Normal weight subgroup is defined as BMI ≤ 25.4, overweight subgroup as BMI > 25.4.
  5. P-values <0.05 were considered as statistical significant.
  6. Controls vs. gallstone carriers: α P = 0.0378, β P = 0.0269 (21%), γ P = 0.0231 (21%), η (16%). No adjustment in the total group.
  7. Normal weight persons vs. overweight individuals: δ P = 0.0028 after adjustment (factor 6) P = 0.0168, ε P = 0.0044 after adjustment P = 0.0264, ζ P = 0.0065 after adjustment P = 0.039.