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Table 3 Impact of patients’ characteristics and comorbidities on adherence and persistence to UC treatments

From: Medication adherence and persistence in the treatment of Canadian ulcerative colitis patients: analyses with the RAMQ database

 

Adherence

Persistence

 

Patient’s adherent over 12 months n (%)

Adjusted OR [95% CI]

Patient’s persistent at 12 months n (%)

Adjusted OR [95% CI]

Sex

    

· Male

222 (30.5)

1.3

365 (50.1)

1.4

· Female

243 (25.5)

[1.05–1.6]

400 (42.0)

[1.1–1.7]

Age

    

· < 60

201 (23.3)

1.6

381 (44.1)

NS

· ≥ 60

264 (32.3)

[1.3–2.0]

384 (49.9)

 

Previous use of corticosteroids

    

· Yes

142 (28.2)

NS

231 (45.8)

NS

· No

323 (27.4)

 

534 (45.4)

 

Concurrent use of corticosteroids

    

· Yes

179 (32.7)

1.4

273 (49.8)

1.4

· No

286 (25.2)

[1.1–1.8]

492 (43.4)

[1.1–1.7]

Heart disease

    

· Yes

210 (30.2)

NS

321 (46.2)

NS

· No

255 (25.9)

 

444 (45.0)

 

Respiratory illness

    

· Yes

153 (26.8)

NS

247 (43.3)

1.2

· No

312 (28.1)

 

518 (46.6)

[1.004–1.548]

Hypertension

    

· Yes

262 (31.1)

NS

403 (47.9)

1.2

· No

203 (24.2)

 

362 (43.1)

[1.01–1.50]

Diabetes

    

· Yes

167 (30.4)

NS

515 (45.5)

NS

· No

298 (26.3)

 

250 (45.5)

 

Chronic disease score

    

· Yes

159 (23.2)

NS

296 (43.3)

NS

· No

306 (30.7)

 

469 (47.0)

 
  1. CI, confidence interval; NS, not significant; OR, odds ratio; UC, ulcerative colitis.