Figure 5

Conventional, NBI-magnification endoscopic and endocytoscopic appearances and histopathological and immunohistological findings in Case 15 of gastric involvement of ATLL. On conventional gastroscopy, there are hyperemic erosions in the antrum (A). NBI-magnification endoscopy shows a slightly irregular distribution and mild dilation of gastric pits with nominal irregularity in the microvascular architecture (B). Endocytoscopy shows focally increased cellular elements with nuclear irregularity in size and configuration between the pits (C) in the affected area, with oval regular pits with nominal cell infiltrate in the uninvolved mucosa (D). Targeted biopsy specimens taken from the lesion show the abnormal neoplastic cells with the characteristic nuclear irregularity in the T-cell lineage (UCHL-1, X200, E).