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Table 1 Associations between SULF2, WRN methylation and clinicopathological factors in gastric tumor

From: Correlation between the methylation of SULF2 and WRN promoter and the irinotecan chemosensitivity in gastric cancer

Clinicopathologic characteristics n WRN methylated WRN unmethylated Pvalue SULF2 methylated SULF2 unmethylated Pvalue
Age(Years old)
> = 60 61 15 46 0.758 15 46 0.294
<60 41 9 32 14 27
sex
Male 75 17 58 0.732 22 53 0.736
Female 27 7 20 7 20
Histology type
Adenocarcinoma 81 20 61 0.659 25 56 0.336
Mucin cells or Signet ring cell type 20 4 16 4 16
Grade
Grade I 4 1 3 0.954 2 2 0.875
Grade II 54 16 38 20 34
Grade III 44 7 37 7 37
Lymphatic invasion
Without lymphatic invasion 27 5 22 0.474 6 21 0.404
With lymphatic invasion 75 19 56 23 52
TNM stage
I-II 39 7 32 0.296 9 30 0.346
III-IV 63 17 46 20 43
  1. A level of p < 0.05 was considered significant.