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Table 1 Associations between SULF2, WRN methylation and clinicopathological factors in gastric tumor

From: Correlation between the methylation of SULF2 and WRN promoter and the irinotecan chemosensitivity in gastric cancer

Clinicopathologic characteristics

n

WRN methylated

WRN unmethylated

Pvalue

SULF2 methylated

SULF2 unmethylated

Pvalue

Age(Years old)

>ā€‰=ā€‰60

61

15

46

0.758

15

46

0.294

<60

41

9

32

14

27

sex

Male

75

17

58

0.732

22

53

0.736

Female

27

7

20

7

20

Histology type

Adenocarcinoma

81

20

61

0.659

25

56

0.336

Mucin cells or Signet ring cell type

20

4

16

4

16

Grade

Grade I

4

1

3

0.954

2

2

0.875

Grade II

54

16

38

20

34

Grade III

44

7

37

7

37

Lymphatic invasion

Without lymphatic invasion

27

5

22

0.474

6

21

0.404

With lymphatic invasion

75

19

56

23

52

TNM stage

I-II

39

7

32

0.296

9

30

0.346

III-IV

63

17

46

20

43

  1. A level of pā€‰<ā€‰0.05 was considered significant.