Dietary saturated and monounsaturated fatty acids seem not to influence the intestinal serotonergic system. Quantitative analysis of the 5-HT content and the TPH1 mRNA expression in the duodenum (A/B). Representative western blots of SERT and 5-HT3AR in the duodenum and quantitative analysis of protein expression are shown (C/D). a
P < 0.05 ANOVA result for effect of different diets compared to C; b compared to SFA. Means ± SEM, n = 5. Abbreviations: C, control; SFA, saturated fatty acids; MUFA, monounsaturated fatty acids; PUFA, polyunsaturated fatty acids; 5-HT, serotonin; 5-HT3AR, 5-HT receptor 3A; SERT, 5-HT reuptake transporter; TPH1, Tryptophanhydroxylase 1.