Limited utilization of serologic testing in patients undergoing duodenal biopsy for celiac disease

BMC Gastroenterology

Table 3 Non-celiac findings in patients with multiple biopsy sites

Non-duodenal findings in patients with positive pre-biopsy serology				Duodenal findings in patients with negative pre-biopsy serology
Finding	Site	N	%	Finding	N	%
Chronic gastritis	S	18	26%	IVA - IEL	17	4%
Active esophagitis	E	3	4%	Focal active inflammation	15	4%
Lymphocytic gastritis	S	2	3%	Peptic injury	11	3%
Helicobacter pylori	S	2	3%	Celiac disease	4	1%
Other gastric	S	2	3%	Chronic duodenitis	3	1%
Reflux, EE	E	2	3%	Intramucosal granulomas	2	1%
Ilietis	I	2	3%	Ulcer	1	0.3%
Active colitis	C	2	3%	Mild increased lymphocytes	1	0.3%
Other colon	C	2	3%
Lymphocytic colitis	C	1	1%

Results were tabulated for 409 patients with pre-biopsy serologic results and multiple biopsy sites. S = stomach. E = esophagus. I = ileum. C = colon. “Other gastric” includes erosive gastritis and a gastric polyp. “Other colon” includes tubular adenoma and mucosal prolapse. % is based on the number of patients in each serologic category.

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