No. | H&N cancer / TNM stage | Location / size (cm) / pathology (TNM stage) of esophagus | Treatment strategy without IEE screening | Treatment strategy with IEE screening |
---|---|---|---|---|
1 | Oropharynx / II | Lower third / 0.3 / LGIN | Tumor excision | Tumor excision + EMR of esophageal lesion |
2 | Hypopharynx / I | Middle third / 0.5 / LGIN | Tumor excision | Tumor excision + EMR of esophageal lesion |
3 | Oropharynx / III | Lower third / 0.5 / LGIN | Tumor excision + LN dissection + Adjuvant CCRT | Tumor excision + EMR of esophageal lesion + Adjuvant CCRT |
4 | Hypopharynx / III | Middle third / 6.0 / SCC (IIA) | Tumor excision + LN dissection + Adjuvant CCRT | Tumor excision + Adjuvant CCRT with RT field involving esophagus |
5 | Larynx / I | Middle / 1.5 / HGIN | Laryngectomy | Laryngectomy + ESD of esophageal lesion |
6 | Larynx / I | Upper / 6.0 / SCC (IB) | Laryngectomy | Laryngectomy + Esophagectomy + Adjuvant CCRT |
7 | Oropharynx / IVA | Upper / 0.6 / SCC (IA) | Neoadjuvant CCRT + Tumor excision + LN dissection | Neoadjuvant CCRT + Tumor excision + Esophagectomy |
8 | Oropharynx / II | Middle / 4.0 / SCC (IA) | Tumor excision + Adjuvant CCRT | Tumor excision + Esophagectomy + Adjuvant CCRT |
9 | Hypopharynx/IVA | Middle / 2.0 / HGIN | Tumor excision + LN dissection + Adjuvant CCRT | Tumor excision + LN dissection + RFA of esophageal lesion + Adjuvant CCRT |
10 | Hypopharynx / IVB | Upper / 1.5 / SCC(IB) | Definitive CCRT | Definitive CCRT with RT field involving the esophagus |
11 | Hypopharynx/III | Middle / 5.0 / SCC (IIIA) | Tumor excision + LN dissection + Adjuvant CCRT | Neoadjuvant CCRT + Tumor excision + LN dissection + Esophagectomy |
12 | Hypopharynx / IVB | Middle / 1.5 / SCC (IIIA) | Definitive CCRT | Definitive CCRT with RT filed involving the esophagus |
13 | Oral cavity / II | Lower / 0.2 / LGIN | Tumor excision | Tumor excision + EMR of esophageal lesion |
14 | Hypopharynx / III | Middle / 0.8 / HGIN | Tumor excision + LN dissection + Adjuvant CCRT | Tumor excision + LN dissection + ESD of esophageal lesion + Adjuvant CCRT |
15 | Oral cavity / I | Upper / 2.0 / SCC ( IB) | Tumor excision | Tumor excision + Esophagectomy |
16 | Oral cavity / II | Middle / 1.0 / SCC (IA) | Tumor excision | Tumor excision + EMR of esophageal lesion |
17 | Oral cavity / IVB | Middle / 2.0 / SCC (IIIA) | Definitive CCRT | Definitive CCRT with RT field involving esophagus |
18 | Hypopharynx / IVA | Upper / 2.0 / SCC (IB) | Tumor excision + LN dissection + Adjuvant CCRT | Tumor excision + LN dissection + Adjuvant CCRT with RT field involving esophagus |
19 | Hypopharynx / IVA | Middle / 0.8 / HGIN | Tumor excision + LN dissection + Adjuvant CCRT | Tumor excision + LN dissection + EMR + Adjuvant CCRT |
20 | Larynx / IVA | Middle / 6.0 / SCC (IB) | Laryngectomy + Adjuvant CCRT | Laryngectomy + Esophagectomy + Adjuvant CCRT |