Presence of esophageal neoplasia*(n=30) No. of patients (%) | Absence of esophageal neoplasia*(n=99) No. of patients (%) | OR (95% CI) | P-value | |
---|---|---|---|---|
Age (years, mean±SD) | 58.76 ± 9.20 | 55.63 ± 9.99 | 1.03 (0.99-1.08) | 0.130 |
<45 | 1 (3.3) | 12 (12.1) | referent | |
45~54 | 10 (33.3) | 40 (40.4) | 3.00 (0.34-26.82) | |
≧55 | 19 (63.3) | 47 (47.5) | 4.85 (0.56-41.94) | 0.077 |
Sex | ||||
Female | 2 (6.7) | 5 (5.1) | referent | |
Male | 28 (93.3) | 94 (94.9) | 0.74 (0.14-4.05) | 0.733 |
BMI (kg/m2, mean±SD) | 21.64 ± 3.37 | 24.30 ± 4.85 | 0.86 (0.77-0.96)+ | 0.008 |
Location of H&N cancer | ||||
Oral cavity | 8 (26.7) | 55 (55.6) | Referent | |
Oropharynx | 6 (20) | 16 (16.2) | 1.50 (0.34-6.59) | 0.591 |
Hypopharynx | 12 (40) | 20 (20.2) | 4.52 (1.46-13.99) | 0.009 |
Larynx | 4 (13.3) | 4 (4.0) | 5.70 (1.08-29.99) | 0.040 |
Nasopharynx | 0 | 4 (4.0) | NA | NA |
Stage of H&N cancer | ||||
I | 4 (13.3) | 19 (19.2) | Referent | |
II | 4 (13.3) | 14 (14.1) | ||
III | 4 (13.3) | 12 (12.1) | 2.30 (0.98-5.42) | 0.056 |
IV | 18 (60.0) | 51 (51.5) | ||
Alcohol drinking | ||||
Non-drinker | 3 (10) | 32 (32.3) | Referent | |
Drinker | 27 (90) | 67 (67.7) | 4.10 (1.16-14.56) | 0.029 |
Light to moderate | 2 (6.7) | 10 (10.1) | 2.13 (0.30-15.12) | |
Heavy | 25 (83.3) | 57 (57.6) | 4.68 (1.26-17.44) | 0.009 |
Betel quid chewing | ||||
Non-chewer | 17 (56.7) | 33 (33.3) | Referent | |
Chewer | 13 (43.3) | 66 (66.7) | 0.37 (0.16-0.84) | 0.018 |
Light to moderate | 4 (13.3) | 31 (31.3) | 0.25 (0.07-0.87) | |
Heavy | 9 (30.0) | 35 (35.4) | 0.50 (0.19-1.30) | 0.108 |
Cigarettes smoking | ||||
Non-smoker | 3 (10) | 18 (18.2) | Referent | |
Smoker | 27 (90) | 81 (81.8) | 1.87 (0.51-6.86) | 0.348 |
Light to moderate | 21 (70) | 60 (60.6) | 2.10 (0.55-7.97) | 0.528 |
Heavy | 6 (20) | 21 (21.2) | 1.71 (0.37-8.05) | |
Number of exposure | ||||
None | 1 | 7 | Referent | |
1 | 1 | 10 | 0.70 (0.03-14.35) | |
2 | 18 | 42 | 3.00 (0.33-27.09) | |
3 | 10 | 40 | 1.75 (0.19-16.29) | 0.680 |