Table 1 Clinical characteristics of the patients with endoscopically suspected Barrett’s esophagus ≥ 1 cm
PPI non-users | PPI users | ||||||
|---|---|---|---|---|---|---|---|
Controls | ESBE ≥ 1 cm | P | Controls | ESBE ≥ 1 cm | P | ||
Number | 840 (69.2) | 68 (5.6) | - | 256 (69.8) | 23 (6.3) | - | |
SIM | - | 19/49 (38.8) | - | - | 8/18 (44.4) | - | |
Patients profile | |||||||
Age, y | 56.2 ± 14.8 | 58.3 ± 13.6 | 0.31 | 63.5 ± 15.3 | 67.5 ± 12.4 | 0.26 | |
Male sex | 464 (55.2) | 47 (69.1) | 0.03 | 129 (50.4) | 14 (60.9) | 0.34 | |
Alcohol drinking | 244 (29.0) | 20 (29.4) | 0.95 | 54 (21.1) | 8 (34.8) | 0.13 | |
Current smoking | 173 (20.6) | 14 (20.6) | 0.99 | 34 (13.3) | 3 (13.0) | > 0.99 | |
GERD symptoms | 126 (15.0) | 12 (17.6) | 0.56 | 74 (28.9) | 9 (39.1) | 0.30 | |
Endoscopic findings | |||||||
Reflux esophagitis | 68 (8.1) | 17 (25.0) | <0.0001 | 22 (8.6) | 8 (34.8) | 0.0001 | |
Gastric atrophy (Open-type) | 158 (18.8) | 16 (23.5) | 0.34 | 96 (37.5) | 6 (26.1) | 0.28 | |