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Table 1 Baseline demographic and clinical characteristics of subjects who maintained the eradicated state by quadruple therapy (EBMT) or moxifloxacin-based triple therapy (MEA)

From: Long-term follow up Helicobacter Pylori reinfection rate after second-line treatment: bismuth-containing quadruple therapy versus moxifloxacin-based triple therapy

Variable category

Total

EBMT

MEA

p-value*

 

(N = 175)

(N = 59)

(N = 116)

 

Gender

(N = 175)

(n = 59)

(n = 116)

 

  Male

(104, 59.4%)

(35, 59.3%)

(69, 59.5%)

0.98

  Female

(71, 40.6%)

(24, 40.7%)

(47, 40.5%)

 

Age (years) (mean ± SD)

(N = 175)

(n = 59)

(n = 116)

0.67

(56.6 ± 9.4)

(56.1 ± 9.3)

(56.8 ± 9.5)

Clinical diagnosis

(N = 175)

(n = 59)

(n = 116)

 

  Early gastric cancer

(40, 22.9%)

(11, 18.6%)

(29, 25.0%)

0.06

  Dysplasia

(19, 10.9%)

(3, 5.1%)

(16, 13.8%)

 

  Peptic ulcer disease

(34, 19.4%)

(17, 28.8%)

(17, 14.7%)

 

  Chronic gastritis

(82, 46.9%)

(28, 47.5%)

(54, 46.6%)

 

Histological AG in either antrum or body

(N = 116)

(n = 37)

(n = 79)

 

  Yes

(67, 57.8%)

(21, 56.8%)

(46, 68.7%)

0.88

  No

(49, 42.2%)

(16, 43.2%)

(33, 41.8%)

 

Histological IM in either antrum or body

(N = 144)

(n = 47)

(n = 97)

 

  Yes

(84, 58.3%)

(23, 48.9%)

(61, 62.9%)

0.11

  No

(60, 41.7%)

(24, 51.1%)

(36, 37.1%)

 
  1. EBMT: esomeprazole (20 mg b.i.d), tripotassium dicitrate bismuthate (300 mg q.i.d), metronidazole (500 mg t.i.d), and tetracycline (500 mg q.i.d); MEA: moxifloxacin (400 mg q.d.), esomeprazole (20 mg b.i.d), and amoxicillin (1000 mg b.i.d.); AG, atrophic gastritis, IM, intestinal metaplasia.
  2. All of early gastric cancer patients were cured by endoscopic submucosal dissection.
  3. *p-value for Pearson chi-square test for comparison of categorical data, and independent samples t-test for comparison of age.