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Table 1 Comparison of general patient characteristics and laboratory parameters between GERD patients with and without T2D

From: Gastro-oesophageal reflux disease in type 2 diabetics: symptom load and pathophysiologic aspects - a retro-pro study

 

T2D GERD patients

Non-diabetic GERD patients

p

Patients (n)

65

130

---

Females (n [%])

29 [44.6%]

58 [44.6%]

n.s.*

Age (years, mean ± SD)

58.6 ± 9.2

58.5 ± 8.8

n.s.**

BMI (kg/m2, mean ± SD)

31.1 ± 5.2

27.7 ± 3.7

<0.001**

Smoking (n [%])

18 [27.7%]

12 [10.1%]

0.002*

Duration of GERD symptoms (years, median [IQR])

5.0 [3.0;10.0]

5.0 [2.0;11.0]

n.s.***

HbA1c (%)

7.2 ± 1.1

5.3 ± 0.9

<0.001**

Total cholesterol (mg/d, mean ± SD)

204.2 ± 44.9

217.3 ± 38.0

0.013***

LDL* (mg/dl, mean ± SD)

126.6 ± 32.6

134.8 ± 36.9

n.s.***

HDL# (mg/dl, mean ± SD)

56.3 ± 16.0

60.2 ± 18.3

n.s.***

Triglycerides (mg/dl, mean ± SD)

183.0 ± 118.9

128.8 ± 66.4

<0.001***

Blood urea nitrogen (mg/dl, mean ± SD)

15.1 ± 4.9

13.7 ± 4.5

n.s.***

Creatinine (mg/dl, mean ± SD)

1.0 ± 0.2

0.9 ± 0.1

n.s.***

  1. n number, SD Standard deviation, IQR Interquartile range, BMI Body mass index, n.s. Not significant; * chi-square test, ** t-test, *** u-test, p p-value.