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Table 1 Comparison of general patient characteristics and laboratory parameters between GERD patients with and without T2D

From: Gastro-oesophageal reflux disease in type 2 diabetics: symptom load and pathophysiologic aspects - a retro-pro study

  T2D GERD patients Non-diabetic GERD patients p
Patients (n) 65 130 ---
Females (n [%]) 29 [44.6%] 58 [44.6%] n.s.*
Age (years, mean ± SD) 58.6 ± 9.2 58.5 ± 8.8 n.s.**
BMI (kg/m2, mean ± SD) 31.1 ± 5.2 27.7 ± 3.7 <0.001**
Smoking (n [%]) 18 [27.7%] 12 [10.1%] 0.002*
Duration of GERD symptoms (years, median [IQR]) 5.0 [3.0;10.0] 5.0 [2.0;11.0] n.s.***
HbA1c (%) 7.2 ± 1.1 5.3 ± 0.9 <0.001**
Total cholesterol (mg/d, mean ± SD) 204.2 ± 44.9 217.3 ± 38.0 0.013***
LDL* (mg/dl, mean ± SD) 126.6 ± 32.6 134.8 ± 36.9 n.s.***
HDL# (mg/dl, mean ± SD) 56.3 ± 16.0 60.2 ± 18.3 n.s.***
Triglycerides (mg/dl, mean ± SD) 183.0 ± 118.9 128.8 ± 66.4 <0.001***
Blood urea nitrogen (mg/dl, mean ± SD) 15.1 ± 4.9 13.7 ± 4.5 n.s.***
Creatinine (mg/dl, mean ± SD) 1.0 ± 0.2 0.9 ± 0.1 n.s.***
  1. n number, SD Standard deviation, IQR Interquartile range, BMI Body mass index, n.s. Not significant; * chi-square test, ** t-test, *** u-test, p p-value.