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Table 3 Comparison of the results obtained with each treatment during the hospitalizations

From: Erythromycin versus neomycin in the treatment of hepatic encephalopathy in cirrhosis: a randomized double-blind study

Variables Erythromycin Neomycin p
IHD 1 3.00 (2.25 : 4.00) 5.00 (3.25 : 11.25) 0.032
∆ GCS 1 1.00 (0.25 : 2.00) 0.00 (0.00 : 3.25) 0.394
∆ MELD 2 −0.55 ± 1.53 −0.62 ± 2.08 0.917
∆ HEG 1 2 (1 : 2.5) 2 (1 : 3) 0.806
∆ HEI 1 −6.00 (−9.00 : -1.50) −5.00 (−7.00 : -1.25) 0.632
∆ CRP 1 0.30 (0.10 : 0.70) 1.10 (0.15 : 4.30) 0.111
∆ NH3 2 −31.40 ± 49.32 −30.70 ± 92.15 0.979
ALT 2 3.20 ± 8.54 3.71 ± 7.12 0.026
∆ AST 2 −15.70 ± 48.06 8.42 ± 21.80 0.678
∆ AP 2 −17.70 ± 65.3 −12.30 ± 48.90 0.802
∆ GGT 1 −7.00 (−29.00 : 0.75) −5.00 (−25.50 : 5.00) 0.724
∆ urea 2 −2.19 ± 20.64 −4.25 ± 23.72 0.802
∆ creatinine 2 −0.10 ± 0.27 −0.20 ± 0.30 0.289
  1. 1 median, 1º : 3º quartiles ; Mann–Whitney test comparison.
  2. 2 mean ± standard deviation ; t test comparison.
  3. ∆ = final – initial values. IHD = in-hospital days. GCS = Glasgow coma scale. HEI = hepatic encephalopathy index. HEG = hepatic encephalopathy grade. CRP = C reactive protein (mg/dl). NH3 = serum ammonia (μM/l). ALT = alanine aminotranspherase, AST = aspartate aminotranspherase, AP = alcaline phosphatase, and GGT = gamma-glutamyltranspeptidase (all in U/l). Urea and creatinine are measured in mg/dl.