Figure 6

Overall survival curves for colorectal cancer (CRC) patients stratified by the Sam68 expression level, according to M classification and tumor differentiation. In the M0 classification (A) and moderately differentiated tumor subgroups (C), patients with low Sam68 expression had significantly better overall survival than patients with high Sam68 expression (P = 0.01). In the M1 classification (B) and poorly differentiated tumor subgroups (D), the overall survival of patients with high and low Sam68 expression was not significantly different. In the M0 classification (E) and moderately differentiated tumor subgroups (G), patients with Sam68 cytoplasmic localization had significantly better overall survival (P = 0.027 and P = 0.024, respectively) than patients with Sam68 nuclear localization. In the M1 classification (F) and poorly differentiated subgroups (H), the overall survival of patients with Sam68 cytoplasmic and nuclear localization was not significantly different.