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Table 3 Regulated genes by combination of H. pylori infection and high-salt diet in mouse gastric mucosa

From: Gene expression analysis of a Helicobacter pylori-infected and high-salt diet-treated mouse gastric tumor model: identification of CD177 as a novel prognostic factor in patients with gastric cancer

Accession no. Symbol Genes/proteins Fold changes
Up-regulated genes
XM_357640 Igk-V8 Immunoglobulin kappa chain variable 8 (V8) 14.4
XM_001472541 Ighg Immunoglobulin heavy chain (gamma polypeptide) 9.2
NM_026862 Cd177 CD177 antigen 7.3
NM_011260 Reg3g Regenerating islet-derived 3 gamma 6.1
NM_023137 Ubd Ubiquitin D 4.3
XM_144817 Igk-V34 Immunoglobulin kappa chain variable 34 (V34) 4.1
NM_007675 Ceacam10 Carcinoembryonic antigen-related cell adhesion molecule 10 3.7
NM_183322 Khdc1a KH domain containing 1A 3.3
NM_011475 Sprr2i Small proline-rich protein 2I 3.2
NM_175165 Tprg Transformation related protein 63 regulated 3.2
NM_175406 Atp6v0d2 ATPase, H+ transporting, lysosomal V0 subunit D2 3.0
NM_009703 Araf v-raf murine sarcoma 3611 viral oncogene homolog 2.6
NM_026822 Lce1b Late cornified envelope 1B 2.5
NM_016958 Krt14 Keratin 14 2.5
NM_212487 Krt78 Keratin 78 2.4
NM_009807 Casp1 Caspase 1 2.4
NM_146037 Kcnk13 Potassium channel, subfamily K, member 13 2.4
NM_019450 Il1f6 Interleukin 1 family, member 6 2.3
NM_008827 Pgf Placental growth factor 2.3
XM_893506 Klk12 Kallikrein related-peptidase 12 2.3
NM_016887 Cldn7 Claudin 7 2.3
NM_029360 Tm4sf5 Transmembrane 4 superfamily member 5 2.2
NM_172301 Ccnb1 Cyclin B1 2.2
NM_010739 Muc13 Mucin 13, epithelial transmembrane 2.2
NM_011165 Prl4a1 Prolactin family 4, subfamily a, member 1 2.2
NM_010162 Ext1 Exostoses (multiple) 1 2.2
NM_011704 Vnn1 Vanin 1 2.1
NM_011082 Pigr Polymeric immunoglobulin receptor 2.1
NM_007769 Dmbt1 Deleted in malignant brain tumors 1 2.1
NM_022984 Retn Resistin 2.1
NM_173037 Tmco 7 Transmembrane and coiled-coil domain 7 2.1
NM_009100 Rptn Repetin 2.1
NM_007630 Ccnb2 Cyclin B2 2.1
NM_001081060 Slc9a3 Solute carrier family 9 (sodium/hydrogen exchanger), member 3 2.0
NM_146588 Olfr1030 Olfactory receptor 1030 2.0
Down-regulated genes
NM_008753 Oaz1 Ornithine decarboxylase antizyme 1 0.31
NM_027126 Hfe2 Hemochromatosis type 2 (juvenile) (human homolog) 0.33
NM_053206 Magee2 Melanoma antigen, family E, 2 0.33
NM_010924 Nnmt Nicotinamide N-methyltransferase 0.41
NM_026260 Tctn3 Tectonic family member 3 0.41
NM_181039 Lphn1 Latrophilin 1 0.43
NM_008312 Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.43
NM_146667 Olfr740 Olfactory receptor 740 0.44
NM_007550 Blm Bloom syndrome homolog (human) 0.44
NM_011243 Rarb Retinoic acid receptor, beta 0.44
NM_184052 Igf1 Insulin-like growth factor 1 0.45
NM_013893 Reg3d Regenerating islet-derived 3 delta 0.46
NM_008645 Mug1 Murinoglobulin 1 0.46
NM_029550 Keg1 Kidney expressed gene 1 0.46
NM_019388 Cd86 CD86 antigen 0.46
NM_011316 Saa4 Serum amyloid A 4 0.47
NM_007811 Cyp26a1 Cytochrome P450, family 26, subfamily a, polypeptide 1 0.47
NM_011538 Tbx6 T-box 6 0.48
NM_011086 Pip5k3 Phosphatidylinositol-3-phospate/phosphatidylinositol 5-kinase, type III 0.48
NM_133723 Asph Aspartate-beta-hydroxylase 0.48
NM_001081390 Palld Palladin, cytoskeletal associated protein 0.48
NM_007858 Diap1 Diaphanous homolog 1 (Drosophila) 0.48
NM_053271 Rims2 Regulating synaptic membrane exocytosis 2 0.48
NM_153163 Cadps2 Ca2+-dependent activator protein for secretion 2 0.49
NM_007541 Bglap1 Bone gamma carboxyglutamate protein 1 0.49
NM_031871 Ghdc GH3 domain containing 0.49
NM_025545 Aptx Aprataxin 0.49
NM_177322 Agtr1a Angiotensin II receptor, type 1a 0.49
NM_026872 Ubap2 Ubiquitin-associated protein 2 0.49
NM_028045 Erv3 Endogenous retroviral sequence 3 0.49
NM_011641 Trp63 Transformation related protein 63 0.49