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Table 3 Regulated genes by combination of H. pylori infection and high-salt diet in mouse gastric mucosa

From: Gene expression analysis of a Helicobacter pylori-infected and high-salt diet-treated mouse gastric tumor model: identification of CD177 as a novel prognostic factor in patients with gastric cancer

Accession no.

Symbol

Genes/proteins

Fold changes

Up-regulated genes

XM_357640

Igk-V8

Immunoglobulin kappa chain variable 8 (V8)

14.4

XM_001472541

Ighg

Immunoglobulin heavy chain (gamma polypeptide)

9.2

NM_026862

Cd177

CD177 antigen

7.3

NM_011260

Reg3g

Regenerating islet-derived 3 gamma

6.1

NM_023137

Ubd

Ubiquitin D

4.3

XM_144817

Igk-V34

Immunoglobulin kappa chain variable 34 (V34)

4.1

NM_007675

Ceacam10

Carcinoembryonic antigen-related cell adhesion molecule 10

3.7

NM_183322

Khdc1a

KH domain containing 1A

3.3

NM_011475

Sprr2i

Small proline-rich protein 2I

3.2

NM_175165

Tprg

Transformation related protein 63 regulated

3.2

NM_175406

Atp6v0d2

ATPase, H+ transporting, lysosomal V0 subunit D2

3.0

NM_009703

Araf

v-raf murine sarcoma 3611 viral oncogene homolog

2.6

NM_026822

Lce1b

Late cornified envelope 1B

2.5

NM_016958

Krt14

Keratin 14

2.5

NM_212487

Krt78

Keratin 78

2.4

NM_009807

Casp1

Caspase 1

2.4

NM_146037

Kcnk13

Potassium channel, subfamily K, member 13

2.4

NM_019450

Il1f6

Interleukin 1 family, member 6

2.3

NM_008827

Pgf

Placental growth factor

2.3

XM_893506

Klk12

Kallikrein related-peptidase 12

2.3

NM_016887

Cldn7

Claudin 7

2.3

NM_029360

Tm4sf5

Transmembrane 4 superfamily member 5

2.2

NM_172301

Ccnb1

Cyclin B1

2.2

NM_010739

Muc13

Mucin 13, epithelial transmembrane

2.2

NM_011165

Prl4a1

Prolactin family 4, subfamily a, member 1

2.2

NM_010162

Ext1

Exostoses (multiple) 1

2.2

NM_011704

Vnn1

Vanin 1

2.1

NM_011082

Pigr

Polymeric immunoglobulin receptor

2.1

NM_007769

Dmbt1

Deleted in malignant brain tumors 1

2.1

NM_022984

Retn

Resistin

2.1

NM_173037

Tmco 7

Transmembrane and coiled-coil domain 7

2.1

NM_009100

Rptn

Repetin

2.1

NM_007630

Ccnb2

Cyclin B2

2.1

NM_001081060

Slc9a3

Solute carrier family 9 (sodium/hydrogen exchanger), member 3

2.0

NM_146588

Olfr1030

Olfactory receptor 1030

2.0

Down-regulated genes

NM_008753

Oaz1

Ornithine decarboxylase antizyme 1

0.31

NM_027126

Hfe2

Hemochromatosis type 2 (juvenile) (human homolog)

0.33

NM_053206

Magee2

Melanoma antigen, family E, 2

0.33

NM_010924

Nnmt

Nicotinamide N-methyltransferase

0.41

NM_026260

Tctn3

Tectonic family member 3

0.41

NM_181039

Lphn1

Latrophilin 1

0.43

NM_008312

Htr2c

5-hydroxytryptamine (serotonin) receptor 2C

0.43

NM_146667

Olfr740

Olfactory receptor 740

0.44

NM_007550

Blm

Bloom syndrome homolog (human)

0.44

NM_011243

Rarb

Retinoic acid receptor, beta

0.44

NM_184052

Igf1

Insulin-like growth factor 1

0.45

NM_013893

Reg3d

Regenerating islet-derived 3 delta

0.46

NM_008645

Mug1

Murinoglobulin 1

0.46

NM_029550

Keg1

Kidney expressed gene 1

0.46

NM_019388

Cd86

CD86 antigen

0.46

NM_011316

Saa4

Serum amyloid A 4

0.47

NM_007811

Cyp26a1

Cytochrome P450, family 26, subfamily a, polypeptide 1

0.47

NM_011538

Tbx6

T-box 6

0.48

NM_011086

Pip5k3

Phosphatidylinositol-3-phospate/phosphatidylinositol 5-kinase, type III

0.48

NM_133723

Asph

Aspartate-beta-hydroxylase

0.48

NM_001081390

Palld

Palladin, cytoskeletal associated protein

0.48

NM_007858

Diap1

Diaphanous homolog 1 (Drosophila)

0.48

NM_053271

Rims2

Regulating synaptic membrane exocytosis 2

0.48

NM_153163

Cadps2

Ca2+-dependent activator protein for secretion 2

0.49

NM_007541

Bglap1

Bone gamma carboxyglutamate protein 1

0.49

NM_031871

Ghdc

GH3 domain containing

0.49

NM_025545

Aptx

Aprataxin

0.49

NM_177322

Agtr1a

Angiotensin II receptor, type 1a

0.49

NM_026872

Ubap2

Ubiquitin-associated protein 2

0.49

NM_028045

Erv3

Endogenous retroviral sequence 3

0.49

NM_011641

Trp63

Transformation related protein 63

0.49