Gene expression analysis of a Helicobacter pylori-infected and high-salt diet-treated mouse gastric tumor model: identification of CD177 as a novel prognostic factor in patients with gastric cancer

Table 2 Incidence and multiplicity of gastric tumors in MNU-treated mice

Group	Effective number	Treatment	Incidence (%)			Multiplicity (no. of tumor/mouse)
Group	Effective number	Treatment	Adenoma	Carcinoma	Total tumor	Adenoma	Carcinoma	Total tumor
A	21	MNU	3(14.3)	13(61.9)	13(61.9)	0.1 ± 0.4^a	0.8 ± 0.7	0.9 ± 0.8
B	4	MNU + H. pylori	4(100)^b	4(100)	4(100)	1.5 ± 0.6	1.8 ± 1.0	3.3 ± 1.0^c
C	14	MNU + 10% NaCl	2(14.3)	6(42.9)	7(50.0)	0.2 ± 0.6	0.8 ± 1.0	1.0 ± 1.2
D	9	MNU + H. pylori + 10% NaCl	4(44.4)	8(88.8)	9(100)^d	0.4 ± 0.5^e	2.1 ±1.4^d	2.6 ± 1.1^d

Values for multiplicity are expressed as means ± SD. Incidences were generally assessed by Chi-square test, followed by pairwise analysis with Bonferroni correction. Multiplicities were generally analyzed by ANOVA, followed by the Tukey test for multiple comparison. ^a P < 0.01 vs. Group B, ^b P < 0.01 vs. Group A, ^c P < 0.05 vs. Group A, ^d P < 0.05 vs. Group C, ^e P <0.05 vs. Group B.

ISSN: 1471-230X