Table 1 Demographic data pH data and endoscopic results for patients before therapy with esomeprazole at baseline assessment
From: GERD assessment including pH metry predicts a high response rate to PPI standard therapy
Screening | pH negative | symptom relief 40 mg q.d. | symptom relief 40 mg b.i.d. | persistence | |
|---|---|---|---|---|---|
n = 31 | n = 9 | n = 19 | n = 2 | n = 1 | |
Gender (male/female) | 12/19 | 0/9 | 9/10 | 2/0 | 1/0 |
Age (mean±SD) | 52.4±17.1 years | 47.5±3.5 years | 52.5± 2.8 years | 23.7± 5.1 years | 66 years |
Endoscopy | |||||
NERD | 7 (no erosions) | 7 | |||
ERD Los Angeles A | 2 | 4 | 1 | 1 | |
ERD Los Angeles B | 5 | 1 | |||
ERD Los Angeles C | 1 | ||||
Barrett’s Esophagus | 2 | ||||
DeMeester score ±SD | _ | 5.5 ± 1.8 | 26.9 ± 3.9 | 20.9 ± 15.7 | 30.3 |
‐ DeMeester [day 1] | _ | 5.9 ± 2.9 | 28.2 ± 4.8 | 21.6 ± 19.8 | 23.2 |
‐ DeMeester [day 2] | _ | 4.9 ± 2.4 | 25.6 ± 3.9 | 10.7 ± 3.5 | 34.8 |