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Table 5 Cultivation and enumeration of Lactococcus lactis in cecal mucosa and stool of Clostridium difficile -infected hamsters

From: The protective effect of recombinant Lactococcus lactis oral vaccine on a Clostridium difficile-infected animal model

Group (n = 8 each)

L. lactisin cecal mucosa

L. lactisfrom stool (106CFU/g)

 
 

(104CFU/g)

Day 7

Day 14

Control group

0.413 ± 0.1

Fungi*

 

Empty plasmid group

104.75 ± 8.41 ab

109 ± 6.95 e

69.38 ± 6.44dc

Secreted-protein plasmid group

108.25 ± 4.57 ab

124.63 ± 7.92 e

64.38 ± 6.37dc

Membrane-anchored plasmid group

105 ± 3.9 ab

104 ± 3.45 e

53.75 ± 4.30dc

  1. a compared with control group (F=96.289, P=0.000); b compared among immunization groups (F=0.107, P=0.899); e compared among immunization groups (F=0.690, P=0.513); d compared among immunization groups (F=1.9, P=0.174); and c compared between days 7 and 14, P < 0.01. * Grade III dysbacteriosis – appearance of opportunistic flora on top of hemolytic and lactose-negative escherichia, growth of cocci and suppression of lacto- and bifidobacteria (Ladodo scale).
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BMC Gastroenterology

ISSN: 1471-230X

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