Table 4 Appearance of hamster in different groups after Clostridium difficile challenge (n = 8 each)
Manifestations | Control group | Empty plasmid group | Secreted-protein plasmid group | Membrane-anchored plasmid group |
|---|---|---|---|---|
Diarrhea | All on day 1 | All on day 1 | 2 on day 1 | No |
Perianal and tail damp | Yes | Yes | No | No |
Paw and abdomen damp | Six on day 2 | Only one on day 2 | No | No |
Activity | Decreased | Decreased | Normal | Normal |
Response to stimulation | Decreased, even disappeared | Only one weakened | Normal | Normal |
Fur luster | Lackluster | Normal | Normal | Normal |
Eating | Decreased | Almost normal | Normal | Normal |
Death | All | One | No | No |