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Figure 2 | BMC Gastroenterology

Figure 2

From: Synchronous appendiceal and intramucosal gastric signet ring cell carcinomas in an individual with CDH1-associated hereditary diffuse gastric carcinoma: a case report of a novel association and review of the literature

Figure 2

Appendiceal Signet Ring Cell Carcinoma (x 20 magnification). (A) Hematoxylin- and eosin-stained section of appendiceal wall with extensive infiltration by columns and groups of cells having prominent mucin vacuoles and peripheral displacement of nuclei. By immunohistochemistry, the signet ring cells show strong positivity for Cytokeratin 20 (B) and CDX2 (C) and negativity for Cytokeratin 7 (D) and estrogen receptor (E).

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