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Figure 1 | BMC Gastroenterology

Figure 1

From: Synchronous appendiceal and intramucosal gastric signet ring cell carcinomas in an individual with CDH1-associated hereditary diffuse gastric carcinoma: a case report of a novel association and review of the literature

Figure 1

Intramucosal Gastric Signet Ring Cell Carcinoma (x 20 magnification). (A) Hematoxylin- and eosin-stained section of gastric mucosa with a focus of infiltrating cells having prominent mucin vacuoles and peripheral displacement of nuclei. By immunohistochemistry, the signet ring cells show strong positivity for Cytokeratin 7 (B) and Cytokeratin 20 (C), weak positivity for E-cadherin (D), and negativity for CDX2 (E).

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