Figure 5
From: Duodenal microbiota composition and mucosal homeostasis in pediatric celiac disease
The relative expression of zonula occludens 1 (ZO-1) (A) and the scatterplot of ZO-1 and TLR2 expressions (B) in duodenal biopsies. A) Expression of ZO-1 in duodenal biopsies of healthy control children (HC, n = 8), celiac disease children (CD, n = 9) and treated celiac disease adults (T-CD, n = 6). The relative gene expression of ZO-1 is significantly between CD and T-CD (*p < 0.05). Boxplot shows 25th to 75th percentile with a line at median and the whiskers represent interquartile range. Samples, which are outside 1.5 times the interquartile range above the upper quartile (3rd quartile) and below the lower quartile (1st quartile) are denoted by circles. B) The scatterplot of relative expression of ZO-1 and TLR2 in duodenal biopsies of HC. The relationship between ZO-1 and TLR2 expressions is estimated by linear regression, and indicated by dashed line. The effect of slope is significant (p = 0.02), having coefficient of determination (R2) of 0.63.